69129-28-8

Basic information

• Product Name: 2-Piperidinecarboxylic acid, 1-[2-amino-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methyl-, ethyl ester, monohydrochloride
• CAS NO: 69129-28-8
• Molecular Formula: C15H28N6O5.ClH
• Molecular Weight: 408.885
• Mol File: 69129-28-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Piperidinecarboxylic acid, 1-[2-amino-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methyl-, ethyl ester, monohydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Piperidinecarboxylic acid, 1-[2-amino-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methyl-, ethyl ester, monohydrochloride(69129-28-8)
• EPA Substance Registry System: 2-Piperidinecarboxylic acid, 1-[2-amino-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methyl-, ethyl ester, monohydrochloride(69129-28-8)

Safety Data

• Hazardous Substances Data: 69129-28-8(Hazardous Substances Data)

Upstream product

• 74863-81-3 ethyl 1-α-(tert-butoxycarbonyl)-N^ω-nitro-L-arginyl>-4-methyl-2-piperidinecarboxylate 
• 2188-18-3 Boc-Arg(NO₂)-OH 
• 66937-93-7 4(R)-Methylpiperidine-2(R)-carboxylic acid ethyl ester 

Relevant articles and documents

Thrombin inhibitors. 3. Carboxyl-containing amide derivatives of N alpha-substituted L-arginine.

A series of N alpha-(arylsulfonyl)-L-arginine amide derivatives having carboxamide N-substituents with a carboxyl group was prepared and tested as inhibitors of the clotting activity of thrombin. The most inhibitory compounds were obtained when a carboxyl group was introduced into the carbon next to the amide nitrogen of N alpha-(arylsulfonyl)-L-arginine amide derivatives, e.g., N alpha-(arylsulfonyl)-L-arginyl-N-butyl-, N-(methoxyethyl)- or N-(tetrahydrofurfuryl)glycine and 4-alkyl-1-[N alpha-(arylsulfonyl)-L-arginyl]-2-piperidinecarboxylic acid, with an I50 of 1-3 X 10(-7) M.