69617-43-2

Basic information

• Product Name: (2-bromophenyl-4-methyl)phenylmethanone
• Synonyms: (2-bromophenyl-4-methyl)phenylmethanone
• CAS NO: 69617-43-2
• Molecular Weight: 275.145
• Mol File: 69617-43-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (2-bromophenyl-4-methyl)phenylmethanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-bromophenyl-4-methyl)phenylmethanone(69617-43-2)
• EPA Substance Registry System: (2-bromophenyl-4-methyl)phenylmethanone(69617-43-2)

Safety Data

• Hazardous Substances Data: 69617-43-2(Hazardous Substances Data)

Upstream product

• 95-46-5 2-methylphenyl bromide 
• 98-88-4 benzoyl chloride 
• 7697-27-0 2-bromo-4-methylbenzoic acid 
• 75-15-0 carbon disulfide 
• 7446-70-0 aluminium trichloride 
• 938461-09-7 2-bromo-N-methoxy-N,4-dimethylbenzamide 
• 100-58-3 phenylmagnesium bromide 
• 53456-09-0 4-methyl-2-bromobenzoyl chloride 
• 108-86-1 bromobenzene 
• 71-43-2 benzene 
• 824-54-4 2-bromo-4-methylbenzaldehyde 

Downstream Products

• 861781-39-7 2-(2,4-dinitro-anilino)-4-methyl-benzophenone 
• 15832-68-5 (S)-neobenodine 
• 84-54-8 2-methylanthracene-9,10-dione 
• 767288-57-3 2-bromo-4-methylbenzophenone 4-methylphenylsulfonylhydrazone 
• 40786-99-0 4-benzoyl-1,3-benzenedicarboxylic acid 
• 611-95-0 4-carboxybenzophenone 
• 1147-41-7 4-methylbenzophenone-2-carboxylic acid 

Relevant articles and documents

Highly Enantioselective Cobalt-Catalyzed Hydroboration of Diaryl Ketones

A highly enantioselective cobalt-catalyzed hydroboration of diaryl ketones with pinacolborane was developed using chiral imidazole iminopyridine as a ligand to access chiral benzhydrols in good to excellent yields and ee. This protocol could be carried out in a gram scale under mild reaction conditions with good functional group tolerance. Chiral biologically active 3-substituted phthalide and (S)-neobenodine could be easily constructed through asymmetric hydroboration as a key step.

Synthesis of Substituted Naphthalenes by 1,4-Palladium Migration Involved Annulation with Internal Alkynes

The palladium catalyzed annulation of 1-bromo-2-vinylbenzene derivatives with internal alkynes was realized for the efficient synthesis of substituted naphthalenes. A controllable aryl to vinylic 1,4-palladium migration process is the key for success.

Synthesis of 3-substituted indazoles and benzoisoxazoles via Pd-catalyzed cyclization reactions: application to the synthesis of nigellicine

Syntheses of 3-substituted indazoles and benzoisoxazoles were efficiently accomplished with the aid of Pd-catalyzed intramolecular carbon-nitrogen and carbon-oxygen bond formations. The catalyst system described herein allows the cyclization to proceed under very mild conditions and thus could be applied to a wide range of substrates with acid- or base-sensitive functional groups. A total synthesis for the indazole ring-containing natural product nigellicine is also described.