70855-13-9Relevant articles and documents
Pd(0)-Catalyzed Conjugate Addition of Benzylzinc Chlorides to α,β-Enones in An Atmosphere of Carbon Monoxide: Preparation of 1,4-Diketones
Yuguchi, Motoki,Tokuda, Masao,Orito, Kazuhiko
, p. 908 - 914 (2007/10/03)
Pd(0)-catalyzed conjugate addition of benzylzine chloride to methyl vinyl ketone in the presence of chlorotrimethylsilane and lithium chloride in an atmosphere of carbon monoxide at room temperature afforded 1-phenyl-2,5-hexanedione monosilyl enol ether. In this catalytic carbonylation, four components are connected in one reaction. Successive acidic workup generated a variety of 1,4-diketones from substituted benzylzine chlorides or related compounds and α,β-enones. Some products were converted to cyclopentenones or five-membered heterocyclic compounds containing an N, O, or S atom.
A facile synthesis of 1,4-diketones
Bergman,Nilsson,Wickberg
, p. 2783 - 2786 (2007/10/02)
1,4-Diketones may conveniently be synthesized by the addition of 2-methylcyclopropenyllithium to N-methoxy-N-methylcarboxamides followed by hydrolysis of intermediate cyclopropyl ketone adducts on silica gel. The new method has been applied to the synthesis of cis-jasmone.
AN IMPROVED, SIMPLE SYNTHESIS OF 3-METHYL-2-(4-METHYLPHENYL) CYCLOPENTEN-2-ONE: AN IMPORTANT INTERMEDIATE IN CUPARENE SYNTHESIS
Ballini, Roberto,Petrini, Marino,Marotta, Emanuela
, p. 543 - 548 (2007/10/02)
Conjugate addition of phenyl-1-methyl-4-(2-nitroethyl) to methyl vinyl ketone in presence of basic alumina, following by Nef reaction and basic cyclization, affords 3-methyl-2-(4-methyl phenyl) cyclopenten-2-one in good yield.