7559-36-6

Basic information

• Product Name: TRANS-4-METHYL-BETA-NITROSTYRENE
• Synonyms: 4'-METHYL-BETA-NITROSTYRENE;4-METHYL-OMEGA-NITROSTYRENE;4-METHYL-W-NITROSTYRENE;1-(P-TOLYL)-2-NITROETHYLENE;1-METHYL-4-(2-NITROVINYL)BENZENE;1-(4-METHYLPHENYL)-2-NITROETHENE;1-(4-METHYLPHENYL)-2-NITROETHYLENE;TRANS-4-METHYL-BETA-NITROSTYRENE
• CAS NO: 7559-36-6
• Molecular Formula: C₉H₉NO₂
• Molecular Weight: 163.17
• Mol File: 7559-36-6.mol
• Article Data: 68

Chemical Properties

• Melting Point: 102-104 °C(lit.)
• Boiling Point: 275.0±9.0 °C(Predicted)
• Appearance: /
• Density: 1.141±0.06 g/cm3(Predicted)
• CAS DataBase Reference: TRANS-4-METHYL-BETA-NITROSTYRENE(CAS DataBase Reference)
• NIST Chemistry Reference: TRANS-4-METHYL-BETA-NITROSTYRENE(7559-36-6)
• EPA Substance Registry System: TRANS-4-METHYL-BETA-NITROSTYRENE(7559-36-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 7559-36-6(Hazardous Substances Data)

Usage

General Description

TRANS-4-METHYL-BETA-NITROSTYRENE is a chemical compound with the molecular formula C9H9NO2. It is a yellow crystalline solid, and its structure consists of a nitro group attached to a beta carbon of a styrene molecule in a trans configuration, with a methyl group substituent. TRANS-4-METHYL-BETA-NITROSTYRENE is often used in organic synthesis as a precursor for other compounds and as a building block for the synthesis of pharmaceuticals and agrochemicals. It is also known for its potential application as an antiproliferative agent in cancer treatment and has been the subject of research for its pharmacological properties. However, it is important to handle TRANS-4-METHYL-BETA-NITROSTYRENE with caution as it is considered to be hazardous and potentially toxic.

Upstream product

• 75-52-5 nitromethane 
• 104-87-0 4-methyl-benzaldehyde 
• 135711-34-1 Butyl-(2-nitro-1-p-tolyl-ethyl)-amine 
• 7559-37-7 1-bromo-1-nitro-2-(4-tolyl)ethene 
• 622-97-9 1-ethenyl-4-methylbenzene 
• 123-08-0 4-hydroxy-benzaldehyde 
• 5736-88-9 p-butoxybenzaldehyde 
• 30669-07-9 4-methoxy-N-[(4-methylphenyl)methylidene]aniline 
• 3395-83-3 4-methylbenzaldehyde dimethylacetal 
• 1355229-73-0 5-(4-methylphenyl)-2-[1-(4-methylphenyl)-2-nitroethoxy]-1,2-oxazolidine-3,3-dicarbonitrile 
• 1866-39-3 4-methylcinnamic acid 
• 28691-43-2 1-(4-methylphenyl)-2-nitroethanol 
• 1866-39-3 trans-p-methylcinnamic acid 
• 104-84-7 para-methylbenzylamine 

Downstream Products

• 22013-87-2 (Z)-1-(2-chloro-2-nitrovinyl)-4-methylbenzene 
• 23211-39-4 1-(1,2-dibromo-2-nitro-ethyl)-4-methyl-benzene 
• 98879-70-0 4-methyl-2,β-dinitro-styrene 
• 858805-53-5 4-methyl-3,β-dinitro-styrene 
• 73256-40-3 bis-(4-methyl-benzylidene)-p-phenylenediamine 
• 113495-53-7 7-methoxy-2-p-tolyl-3-nitro-2H-chromene 
• 95792-98-6 6-methoxy-3-nitro-2-(p-tolyl)-2H-chromene 
• 92774-85-1 3-Hydroxy-2-(2-nitro-1-p-tolyl-ethyl)-cyclopent-2-enone 
• 143357-64-6 N,N-Dimethyl-N'-[3-nitro-2-p-tolyl-prop-(E)-ylidene]-hydrazine 
• 87361-70-4 diethyl α-cyano-p-methylbenzylphosphonate 
• 138964-41-7 3-nitro-4-tolylpyrrole 
• 141367-59-1 2-(2-Benzyloxy-phenyl)-1-phenyl-4-p-tolyl-1H-pyrrole-3-carboxylic acid ethyl ester 
• 141381-42-2 2-(2-Benzyloxy-phenyl)-1-(3,5-dimethyl-phenyl)-4-p-tolyl-1H-pyrrole-3-carboxylic acid ethyl ester 
• 124344-87-2 1-methyl-3-(D-galacto-pentitol-1-yl)-5-(p-tolyl)pyrazole 

Relevant articles and documents

Green sustainable approach for carbon–carbon bond-forming reactions using FeNPs/DETA@rGO nano-catalyst

We have fabricated eccentric highly persuasive bifunctional FeNPs/DETA@rGO (where DETA = diethylenetriamine) nano-catalyst with a dual activation mechanism by presenting aliphatic amine on the basal and/or edges sites offering a base characteristic and Fe

Organocatalytic Asymmetric Synthesis of Aza-Spirooxindoles via Michael/Friedel-Crafts Cascade Reaction of 1,3-Nitroenynes and 3-Pyrrolyloxindoles

An asymmetric [3+3] cyclization of nitroenynes and 3-pyrrolyloxindoles has been realized with a chiral bifunctional squaramide catalyst. This Michael/Friedel-Crafts cascade strategy provides a facile and efficient access to enantioenriched polycyclic aza-spirooxindoles with 32-95% isolated yields and excellent stereocontrol under mild reaction conditions.

Co-Polymeric Nanosponges from Cellulose Biomass as Heterogeneous Catalysts for amine-catalyzed Organic Reactions

Heterogeneous catalysts prepared from biomass waste sources are attracting increasing interest. The reasons rely on the possibility of combining the virtuous approach of circular economy with the consolidated advantages of heterogeneous catalysis, namely the recycling of the system and the possibility to drive selectivity towards desired products. Herein we report a highly porous cellulose-based nanosponge (CNS) and its use as a recoverable catalyst for Henry and Knoevenagel reactions, two classical amino-catalyzed transformations. The material is obtained by cross-linking between TEMPO-oxidized cellulose nanofibers (TOCNF) and branched polyethyleneimine 25 kDa (bPEI) in the presence of citric acid. CNS have been developed as sorbent materials for water remediation but their use as heterogeneous catalysts was never investigated. The fully characterized micro- and nano-porous system guarantees a complete penetration of CNS, allowing reagents to diffuse within. Indeed, by modulating reaction conditions (catalyst loading, temperature, solvent, microwave versus conventional heating, relative ratio of reagents) it was possible to drive selectivity towards the desired products, while maintaining high efficiency in terms of conversion. The catalyst could be re-used several times without losing in catalytic efficiency. In most cases the products’ distribution is quite different from homogeneous conditions, this much more emphasizing the importance of this heterogeneous solution.