7170-40-3

Basic information

• Product Name: 5-PHENOXY-N-VALERIC ACID
• Synonyms: 5-PHENOXY-N-VALERIC ACID;5-PHENOXYPENTANOIC ACID;Phenoxyvalericacid;5-PHENOXY-N-VALERIC ACID 98+%;5-Phenoxyvaleric Acid
• CAS NO: 7170-40-3
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.23
• Mol File: 7170-40-3.mol
• Article Data: 6

Chemical Properties

• Melting Point: 63 °C
• Boiling Point: 165 °C / 2mmHg
• Appearance: /
• Density: 1.115±0.06 g/cm3(Predicted)
• PKA: 4.66±0.10(Predicted)
• CAS DataBase Reference: 5-PHENOXY-N-VALERIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-PHENOXY-N-VALERIC ACID(7170-40-3)
• EPA Substance Registry System: 5-PHENOXY-N-VALERIC ACID(7170-40-3)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 7170-40-3(Hazardous Substances Data)

Usage

General Description

5-Phenoxy-N-valeric acid, also known as valsartan, is a chemical compound that is commonly used in the treatment of high blood pressure and heart failure. It belongs to a class of drugs called angiotensin II receptor blockers (ARBs), which work by relaxing blood vessels so that blood can flow more easily. Valsartan is also used to improve the symptoms of heart failure and to reduce the risk of death in people who have had a heart attack. It is usually taken orally and is available in tablet form. While generally well-tolerated, valsartan can have potential side effects, including dizziness, lightheadedness, and low blood pressure. It is important to consult a healthcare professional before using this medication.

Upstream product

• 74972-56-8 (hex-5-en-1-yloxy)benzene 
• 69687-95-2 ethyl 5-(phenoxy)pentanoate 
• 854879-95-1 2-(3-phenoxy-propyl)-acetoacetic acid ethyl ester 
• 63258-09-3 (3-phenoxy-propyl)-malonic acid 
• 124-38-9 carbon dioxide 
• 1200-03-9 4-bromophenyl butyl ether 
• 5454-83-1 5-bromovaleric acid methyl ester 
• 108-95-2 phenol 
• 139-02-6 sodium phenoxide 
• 6345-89-7 (3-phenoxypropyl)diethyl propanedioate 
• 588-63-6 3-phenoxypropyl bromide 
• 3384-04-1 3-chloropropyl phenyl ether 
• 1927-71-5 4-phenoxybutan-1-ol 
• 2653-89-6 4-phenoxy-1-butene 

Downstream Products

• 69687-95-2 ethyl 5-(phenoxy)pentanoate 
• 2067-33-6 5-bromopentanoic acid 
• 214417-36-4 5-phenoxy-valeryl chloride 
• 16654-52-7 5-phenoxy-1-pentanol 
• 61797-44-2 5-Phenoxy-pentanoic acid methyl-{2-[methyl-(5-phenoxy-pentanoyl)-amino]-ethyl}-amide 
• 108-95-2 phenol 
• 75736-50-4 1-Brom-<5,5,5-D3>pentan 
• 55320-69-9 6,6,6-trideuteriohexanoic acid 
• 84615-44-1 1-Phenoxy-<5,5,5-D3>pentan 
• 84615-43-0 p-Toluolsulfonsaeure-(5-phenoxy-<1,1-D2>pentylester) 
• 51795-98-3 1-bromo-7-phenoxyheptane 
• 22921-72-8 (5-bromopentoxy)benzene 
• 7170-42-5 7-phenoxy-heptanoic acid 
• 92865-48-0 (5-phenoxy-pentyl)-malonic acid 

Relevant articles and documents

2-AMINO-1,3,4-THIADIAZINE AND 2-AMINO-1,3,4-OXADIAZINE BASED ANTIFUNGAL AGENTS

The invention provides a compound which is a diazine of formula (I) or a tautomer thereof, or a pharmaceutically acceptable salt thereof, for use as an antifungal agent: (I) wherein X, N', C', A and E are as defined herein. The invention also provides a compound of Formula (I) as defined herein.

FATTY ACID AMIDE HYDROLASE INHIBITORS

Disclosed are compounds of formula R-X-Y that may be used to inhibit the action of fatty acid amide hydrolase (FAAH). Inhibition of fatty acid amide hydrolase (FAAH) will slow the normal degradation and inactivation of endogenous cannabinoid ligands by FAAH hydrolysis and allow higher levels of those endogenous cannabinergic ligands to remain present. These higher levels of endocannabinoid ligands provide increased stimulation of the cannabinoid CBl and CB2 receptors and produce physiological effects related to the activation of the cannabinoid receptors. They will also enhance the effects of other exogenous cannabinergic ligands and allow them to produce their effects at lower concentrations as compared to systems in which fatty acid amide hydrolase (FAAH) action is hot inhibited. Thus, a compound that inhibits the inactivation of endogenous cannabinoid ligands by fatty acid amide hydrolase (FAAH) may increase the levels of endocannabinoids and, thus, enhance the activation of cannabinoid receptors. Thus, the compound may not directly modulate the cannabinoid receptors but has the effect of indirectly stimulating the cannabinoid receptors by increasing the levels of endocannabinoid ligands. It may also enhance the effects and duration of action of other exogenous cannabinergic ligands that are administered in order to elicit a cannabinergic response.

Pseudo One-Step Cleavage of C-C Bonds in the Decomposition of Ionized Carboxyclic Acids. Radical Like Reactions in Mass Spectrometry

Metastable molecular ions of hexanoic acid (1) decompose unimolecularly to C2H5. and protonated methacrylic acid (5-H+)(92percent rel. abund.).Investigation of the mechanism reveals that 1) the branched cation radical 11 must be regarded as the essential intermediate in the course of the rearrangement/dissociation reaction and 2) the process commences with intramolecular hydrogen transfer from either C-3 or C-5 to the ionized carbonyl oxygen ("hidden" hydrogen migration).Hydrogen transfer from C-4, which would correspond to the well-known McLafferty rearrangement, is of no importance in the C2H5.-elimination from 1.The same conclusion applies for various alternative mechanisms, as for example a SRi type reaction, 1 -> 2-H+.The gas phase chemistry of the cation radical of 1, and in particular the hydrogen exchange processes between the methylene groups C-2/C-3 and C-5/C-6, is in surprisingly close correspondence to the chemistry of free alkyl radicals. - The syntheses of various 13C and 2H-labelled model compounds are described.