7397-16-2

Basic information

• Product Name: (4-methoxy-phenyl)-glyoxal-bis-phenylhydrazone
• Synonyms: (4-methoxy-phenyl)-glyoxal-bis-phenylhydrazone
• CAS NO: 7397-16-2
• Molecular Weight: 344.416
• Mol File: 7397-16-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-methoxy-phenyl)-glyoxal-bis-phenylhydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-methoxy-phenyl)-glyoxal-bis-phenylhydrazone(7397-16-2)
• EPA Substance Registry System: (4-methoxy-phenyl)-glyoxal-bis-phenylhydrazone(7397-16-2)

Safety Data

• Hazardous Substances Data: 7397-16-2(Hazardous Substances Data)

Upstream product

• 6832-17-3 2-diazo-1-(4-methoxyphenyl)ethanone 
• 100-63-0 phenylhydrazine 
• 13664-92-1 2,2-dibromo-1-(4-methoxyphenyl)ethanone 
• 100-06-1 1-(4-methoxyphenyl)ethanone 

Relevant articles and documents

α,α-dibromoketones as useful precursors in organic synthesis: A simple and efficient synthesis of 2,4-diaryl- 1,2,3-triazoles via oxidative cyclization of bisphenylhydrazones

α,α-Dibromoacetophenones (1a-1f) on reaction with phenylhydrazine afford corresponding arylglyoxal bisphenylhydrazones (2a-2f). The oxidation of bishydrazones 2a-2f by using copper(II) chloride in acetic acid leads to intramolecular cyclization with the formation of 2,4-diaryl-1,2,3-triazoles (3a-3f). The method for the conversion 1 → 3 has been simplified by developing one-pot procedure without isolation of intermediates 2.