77249-33-3

Basic information

• Product Name: 2,5-Cyclohexadien-1-one, 4-fluoro-4-methyl-
• CAS NO: 77249-33-3
• Molecular Formula: C7H7FO
• Molecular Weight: 126.13
• Mol File: 77249-33-3.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 2,5-Cyclohexadien-1-one, 4-fluoro-4-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Cyclohexadien-1-one, 4-fluoro-4-methyl-(77249-33-3)
• EPA Substance Registry System: 2,5-Cyclohexadien-1-one, 4-fluoro-4-methyl-(77249-33-3)

Safety Data

• Hazardous Substances Data: 77249-33-3(Hazardous Substances Data)

Upstream product

• 75-05-8 acetonitrile 
• 834-25-3 4-methylphenyl benzyl ether 
• 22921-10-4 p-cresyl isopropyl ether 
• 622-60-6 1-ethoxy-4-methylbenzene 
• 15359-98-5 4-(tert-butoxy)toluene 
• 106-44-5 p-cresol 
• 104-93-8 p-methylanizole 
• 1309-60-0 lead(IV) oxide 

Downstream Products

• 177083-16-8 (4S*,4aS*,4bS*,8aS*,9aR*)-4-fluoro-9-(4-methoxyphenyl)-4,8a-dimethyl-4b,5,6,7,8,9a-hexahydro-4b,9-etheno-4bH-fluoren-1(4H)-one 

Relevant articles and documents

Solvent-Free Fluorination of Electron-Rich Aromatic Compounds with F-TEDA-BF4: Toward “Dry” Processes

An effective protocol for the solvent-free fluorination of electron-rich aromatic compounds with 1-chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate) (F-TEDA-BF4) is described. The protocol allows the easy and efficie

4-Fluorocyclohexa-2,5-dienones as new acceptors for the Hauser annulation

4-Fluorocyclohexa-2,5-dienones are introduced as new acceptors for the Hauser annulation. In cases where the corresponding methoxy analogs fail to undergo annulation, the former smoothly do so with phenylsulfonyl phthalides to furnish anthraquinones in go

Efficient oxidative ipso-fluorination of para-substituted phenols using pyridinium polyhydrogen fluoride in combination with hypervalent iodine(III) reagents

Diacetoxyiodobenzene (PIDA) and bis(trifluoroacetoxy)iodobenzene (PIFA) in the presence of pyridinium polyhydrogen fluoride (PPHF) are effective for the fluorination of para-substituted phenols to give a variety of 4-fluorocyclohexa-2,5-dienones in a good yield. (R,S)-1,1′-Bi-5,6,7,8- tetrahydro-2-naphthol (and its monoacetate) yields atropoisomeric fluorocyclohexadienones. The 4-substituted carbamate open-chain phenols were readily converted to fluorohydroindolenone and fluorohydroquinolenone derivatives by intramolecular conjugate addition.