7790-38-7Relevant articles and documents
Synthesis, isolation, and characterization of an organometallic triiodopalladium(IV) complex. quantitative and regioselective synthesis of two C-I reductive elimination products
Vicente, Jose,Arcas, Aurelia,Julia-Hernandez, Francisco,Bautista, Delia
, p. 5339 - 5341 (2011)
Iodine and the pincer complex [Pd(O,N,C-L)I], where L is the monoanionic ligand resulting from deprotonation of the acetyl group of the dimethylmonoketal of 2,6-diacetylpyridine, are in equilibrium at low temperatures with the palladium(IV) complex [Pd(O,N,C-L)I3], which can be isolated at -40 °C and characterized by 1H NMR spectroscopy and X-ray diffraction studies, in spite of its great instability. When the same reaction is carried out at room temperature, a quantitative reductive elimination process occurs, giving L-I, which in the presence of water affords L′-I, resulting from hydrolysis of L-I.
Enantioselektive Katalyse. VII. Komplexe von (P(R,S),3R,4R,P'(R,S))-3,4-Bis(phenylphosphino)pyrrolidinen. Die Darstellung optisch reiner 1,2-Bisphosphanliganden mit vier Stereozentren, die zusaetzliche funktionelle Gruppen enthalten
Nagel, Ulrich,Rieger, Bernhard,Bublewitz, Alexander
, p. 223 - 240 (1989)
Diastereomeric mixtures of the palladium, the platinum, and the rhodium complexes were prepared from -3,4-bis(phenylphosphino)pyrrolidine (1a).The phosphorus atoms in bis(P(R,S),3R,4R,P'(R,S))-1-(t-butoxycarbonyl)-3,4-bis(phenylphos
Reactions of Pd-PEPPSI complexes with protic acids
Chernenko, A. Yu.,Pasyukov,Astakhov,Tafeenko,Chernyshev
, p. 1196 - 1201 (2018/10/15)
The Pd-PEPPSI complexes widely used to catalyze numerous reactions eliminate the pyridine ligand on treatment with protic acids to give binuclear complexes [Pd(NHC)X2]2 with the Pd–X–Pd (X = Cl, Br, I) bridging bonds. The reaction proceeds with high yields (78–98%) and can be regarded as a preparative approach to binuclear complexes. A prolonged heat treatment of either Pd-PEPPSI complexes or binuclear [Pd(NHC)X2]2 complexes in the presence of strong protic acids results in the Pd–NHC bond cleavage to give azolium salts (proligands) and palladium salts.
Ortho palladation and functionalization of L-phenylalanine methyl ester
Vicente, Jose,Saura-Llamas, Isabel,Garcia-Lopez, Jose-Antonio,Calmuschi-Cula, Beatrice,Bautista, Delia
, p. 2768 - 2776 (2008/10/09)
The ortho-metalated complex (S,S)-[Pd2{κ2(C,N)- C6H4CH2CH(CO2Me)NH 2-2}2(μ-Br)2] (1b) can be prepared by refluxing in acetonitrile equimolecular amounts of Pd(OAc)2 and L-phenylalanine methyl ester hydrochloride, followed by addition of an excess of NaBr. Complex 1b reacts with 4-picoline to give the mononuclear derivative (S)-[Pd{κ2(CN)-C6H4CH 2CH(CO2Me)NH2-2}2Br(NC 5H4Me-4)] (2), whose crystal structure has been determined by X-ray diffraction. The precursor of 1b, (S,S)- [Pd2{κ2-(C,N)-C6H4CH 2CH(CO2Me)NH2-2}2(μ-Cl) 2] (1a), could not be isolated in a pure form, but it can be used as the starting material for the synthesis of functionalized derivatives of the phenylalanine methyl ester. Thus, CO and RNC (R = Xy, tBu) insert into the Pd-C bond of 1a to afford, after depalladation, (S)-1-oxo-3- (methoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline (3) and (S)-l-R-3- (methoxycarbonyl)-3,4-dihydroisoquinolinium triflate (R = tBu (4), Xy (5)), respectively. Reaction of complex 1b with bromine or iodine affords trans-(S,S)-[PdBr2{NH2CH(CO2Me)CH 2C6H4-X-2}2] (X = Br (6), I (7)), which further reacts with 1, 10-phenanthroline (phen) to give [PdBr 2(phen)] and (S)-2-X-phenylalanine methyl ester (X = Br (8). I (9)).
