78761-26-9

Basic information

• Product Name: D(-)-AC-ALPHA-PHENYLGLYCINOL
• Synonyms: N-ACETYL-D-PHENYLGLYCINOL;D(-)-AC-ALPHA-PHENYLGLYCINOL;AC-D-PHENYLGLYCINOL;AC-D-PHG-OL;D(-)-Ac-α-phenylglycinol;D(-)-Ac-a-phenylglycinol;Ac-D-phenylglycinol≥ 99% (TLC)
• CAS NO: 78761-26-9
• Molecular Formula: C₁₀H₁₃NO₂
• Molecular Weight: 179.22
• Mol File: 78761-26-9.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• Storage Temp.: -15°C
• CAS DataBase Reference: D(-)-AC-ALPHA-PHENYLGLYCINOL(CAS DataBase Reference)
• NIST Chemistry Reference: D(-)-AC-ALPHA-PHENYLGLYCINOL(78761-26-9)
• EPA Substance Registry System: D(-)-AC-ALPHA-PHENYLGLYCINOL(78761-26-9)

Safety Data

• Hazardous Substances Data: 78761-26-9(Hazardous Substances Data)

Usage

Chemical Properties

Off-whtite powder

Uses

Different sources of media describe the Uses of 78761-26-9 differently. You can refer to the following data:
1. Amino acid antagonist.
2. D(-)-Ac-alpha-phenylglycinol

Upstream product

• 78761-25-8 D-(-)-O,N-Diacetyl-α-phenylglycinol 
• 108-24-7 acetic anhydride 
• 56613-80-0 D-(-)-2-amino-2-phenyl-1-ethanol 
• 56613-80-0 D-2-phenylglycinol 
• 75-36-5 acetyl chloride 
• 100-42-5 styrene 
• 79-15-2 N-bromoacetamide 
• 875-74-1 (R)-phenylglycine 
• 108-22-5 Isopropenyl acetate 
• 141-78-6 ethyl acetate 

Downstream Products

• 87319-83-3 (1'R,3R)-3-Hydroxy-N-(2-hydroxy-1-phenylethyl)-4,4-dimethylpentanamid 
• 87319-87-7 (S)-3-Hydroxy-4,4-dimethyl-pentanoic acid ((R)-2-hydroxy-1-phenyl-ethyl)-amide 
• 78761-35-0 (S)-Acetylamino-(R)-cyclopent-2-enyl-acetic acid 2-acetylamino-2-phenyl-ethyl ester 
• 78761-35-0 (S)-Acetylamino-(S)-cyclopent-2-enyl-acetic acid 2-acetylamino-2-phenyl-ethyl ester 
• 78761-35-0 (R)-Acetylamino-(R)-cyclopent-2-enyl-acetic acid 2-acetylamino-2-phenyl-ethyl ester 
• 78761-35-0 (R)-Acetylamino-(S)-cyclopent-2-enyl-acetic acid 2-acetylamino-2-phenyl-ethyl ester 
• 87319-88-8 (S)-3-Hydroxy-4-methyl-pentanoic acid ((R)-2-hydroxy-1-phenyl-ethyl)-amide 
• 87319-84-4 (1'R,3R)-3-Hydroxy-N-(2-hydroxy-1-phenylethyl)-4-methylpentanamid 
• 87336-56-9 (R)-3-Hydroxy-N-((R)-2-hydroxy-1-phenyl-ethyl)-3-phenyl-butyramide 
• 87336-57-0 (S)-3-Hydroxy-N-((R)-2-hydroxy-1-phenyl-ethyl)-3-phenyl-butyramide 
• 116173-81-0 (R)-2-methyl-4-phenyl-Δ²-oxazoline 
• 532986-26-8 Phosphoric acid (R)-2-acetylamino-2-phenyl-ethyl ester dibenzyl ester 
• 78781-84-7 (S)-2-acetamido-2-cyclohexylacetic acid 
• 78761-32-7 (+)-(2S,1'R)-N-Acetyl-2-(2'-cyclohexenyl)glycin 

Relevant articles and documents

Chemoselective N-acetylation of primary aliphatic amines promoted by pivalic or acetic acid using ethyl acetate as an acetyl donor

The combination of pivalic or acetic acid as a promoter and EtOAc as a solvent and acetyl donor proved to be efficient for the chemoselective N-acetylation of primary aliphatic amines to afford the corresponding acetamides. We developed a simple and convenient approach, which requires mild reaction conditions. Competitive inter- and intramolecular reactions between aliphatic amines, alcohols, and aromatic amines were examined, and chemoselectivity was achieved by adjusting the conditions of the reaction.

Isopropenyl acetate, a remarkable, cheap and acylating agent of amines under solvent- and catalyst-free conditions: A systematic investigation

Isopropenyl acetate was proved to be an efficient reagent for acetylation of amine in the absence of solvent and catalyst. The corresponding acetamides were obtained in very high yields without any purification.

MUSCARINIC AGONISTS

The present invention relates to compounds of Formula (I): which are agonists of the M-1 muscarinic receptor.