79456-30-7

Basic information

• Product Name: 2-Amino-3-bromo-5-(trifluoromethyl)-pyridine
• Synonyms: 2-Amino-3-bromo-5-(trifluorome;3-bromo-5-(trifluoromethyl)pyridine-2-amine;2-Amino-3-bromo-5-(trifluoromethyl)pyridine 98+%;3-Bromo-5-(trifluoromethyl)pyridin-2-amine, 6-Amino-5-bromo-alpha,alpha,alpha-trifluoro-3-picoline;2-Amino-3-bromo-5-(trifluoromethyl)-pyridine;3-Bromo-5-trifluoromethyl-pyridin-2-ylamine ;3-Bromo-5-(trifluoromethyl)pyridin-2-amine
• CAS NO: 79456-30-7
• Molecular Formula: C₆H₄BrF₃N₂
• Molecular Weight: 241.02
• Product Categories: amine|alkyl bromide;Pyridines ,Heterocyclic Acids,Quinolines ,Quinazolines
• Mol File: 79456-30-7.mol
• Article Data: 11

Chemical Properties

• Melting Point: 98-101℃
• Boiling Point: 221.703 °C at 760 mmHg
• Flash Point: 87.883 °C
• Appearance: /
• Density: 1.79 g/cm³
• Vapor Pressure: 0.106mmHg at 25°C
• Refractive Index: 1.525
• Storage Temp.: Room temperature.
• PKA: 1.79±0.49(Predicted)
• CAS DataBase Reference: 2-Amino-3-bromo-5-(trifluoromethyl)-pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-3-bromo-5-(trifluoromethyl)-pyridine(79456-30-7)
• EPA Substance Registry System: 2-Amino-3-bromo-5-(trifluoromethyl)-pyridine(79456-30-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 79456-30-7(Hazardous Substances Data)

Usage

General Description

2-Amino-3-bromo-5-(trifluoromethyl)-pyridine is a chemical compound with the molecular formula C6H4BrF3N2. It is a pyridine derivative with a trifluoromethyl group and a bromine atom attached to the pyridine ring. 2-Amino-3-bromo-5-(trifluoromethyl)-pyridine has potential applications in the pharmaceutical and agrochemical industries as a building block for the synthesis of various biologically active compounds. It can also be used in the development of new materials and as a reagent in organic synthesis. The trifluoromethyl group in the molecule is known for its role in enhancing the lipophilicity and metabolic stability of bioactive compounds, making 2-Amino-3-bromo-5-(trifluoromethyl)-pyridine a valuable intermediate for the preparation of medicinal and agricultural products.

InChI:InChI=1/C6H4BrF3N2/c7-4-1-3(6(8,9)10)2-12-5(4)11/h1-2H,(H2,11,12)

Upstream product

• 74784-70-6 2-amino-5-trifluoromethylpyridine 
• 79456-29-4 3,6-dichloro-5-(trifluoromethyl)pyridin-2-amine 
• 13534-99-1 2-Amino-3-bromopyridine 
• 887144-94-7 Togni's reagent II 

Downstream Products

• 202409-73-2 2-amino-3-[4-(methylthio)phenyl]-5-trifluoromethyl-pyridine 
• 202409-76-5 2-bromo-3-[4-(methylsulfonyl)phenyl]-5-trifluoromethyl-pyridine 
• 202409-75-4 2-chloro-3-[4-(methylsulfonyl)phenyl]-5-trifluoromethyl-pyridine 
• 71701-92-3 2-chloro-3-bromo-5-(trifluoromethyl)pyridine 
• 847985-20-0 3-(phenylethynyl)-5-(trifluoromethyl)pyridin-2-amine 
• 1211514-97-4 2-amino-3-cyano-5-trifluoromethylpyridine 
• 107867-51-6 5-(trifluoromethyl)-2,3-pyridinediamine 

Relevant articles and documents

Transition metal-free direct C–H trifluoromethyltion of (hetero)arenes with Togni's reagent

A new transition-metal-free direct C–H trifluoromethylation reaction of (hetero)arenes with Togni's reagent was developed. This transformation proceeded smoothly under mild conditions and exhibited good tolerance of many synthetically relevant functional groups. It provided an alternative approach for the synthesis of trifluoromethylated (hetero)arenes.

PEST CONTROL COMPOSITION FOR HARMFUL ARTHROPODS, AND PEST CONTROL METHOD FOR HARMFUL ARTHROPODS

A harmful arthropod control composition comprising a compound represented by the following Formula (1) wherein each symbol represents definitions described in the specification, and one or more fungicidal compounds, which are selected from among azoles, s

2,3,5-TRISUBSTITUTED PYRIDINES AS INHIBITORS OF CYCLOOXYGENASE-2

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