807370-40-7

Basic information

• Product Name: 2'-[N,N-bis(2-methoxyoxalylaminoethyl)aminoethyl]-5'-O-(4,4'-dimethoxytrityl)aminooxalylamino-2'-deoxyuridine
• Synonyms: 2'-[N,N-bis(2-methoxyoxalylaminoethyl)aminoethyl]-5'-O-(4,4'-dimethoxytrityl)aminooxalylamino-2'-deoxyuridine
• CAS NO: 807370-40-7
• Molecular Weight: 917.927
• Mol File: 807370-40-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2'-[N,N-bis(2-methoxyoxalylaminoethyl)aminoethyl]-5'-O-(4,4'-dimethoxytrityl)aminooxalylamino-2'-deoxyuridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-[N,N-bis(2-methoxyoxalylaminoethyl)aminoethyl]-5'-O-(4,4'-dimethoxytrityl)aminooxalylamino-2'-deoxyuridine(807370-40-7)
• EPA Substance Registry System: 2'-[N,N-bis(2-methoxyoxalylaminoethyl)aminoethyl]-5'-O-(4,4'-dimethoxytrityl)aminooxalylamino-2'-deoxyuridine(807370-40-7)

Safety Data

• Hazardous Substances Data: 807370-40-7(Hazardous Substances Data)

Upstream product

• 553-90-2 Dimethyl oxalate 
• 26929-65-7 2'-azido-2'-deoxyuridine 
• 26889-39-4 1-(2-amino-2-deoxy-β-D-ribofuranosyl)uracil 
• 51989-21-0 (2R,3R,4S,5R)-N-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-3-yl)-2,2,2-trifluoroacetamide 
• 177980-12-0 5'-O-(4,4'-dimethoxytrityl)-2'-methoxyoxalylamido-2'-deoxyuridine 
• 174221-86-4 5'-O-dimethoxytrityl-2'-amino-2'-deoxyuridine 
• 694495-30-2 tris(2-methoxyoxalylaminoethyl)amine 

Relevant articles and documents

Monomers for oligonucleotide synthesis with linkers carrying reactive residues: II. The synthesis of phosphoamidites on the basis of uridine and cytosine and containing a linker with methoxyoxalamide groups in position 2′

A convenient preparative synthesis of 2′-amino-2′-deoxyuridine was developed. Starting from 2′-amino-2′-deoxyuridine and 2′-amino-2′-deoxycytidine, monomers for the phosphoamidite oligonucleotide synthesis were obtained that carry a linker with methoxyoxalamide groups in position 2′.