80909-96-2

Basic information

• Product Name: TERT-BUTYL N-[3-(TOSYLOXY)PROPYL]CARBAMATE
• Synonyms: TERT-BUTYL N-[3-(TOSYLOXY)PROPYL]CARBAMATE;3-[(tert-Butoxycarbonyl)amino]propyl 4-methylbenzenesulfonate
• CAS NO: 80909-96-2
• Molecular Formula: C₁₅H₂₃NO₅S
• Molecular Weight: 329.41
• Mol File: 80909-96-2.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• CAS DataBase Reference: TERT-BUTYL N-[3-(TOSYLOXY)PROPYL]CARBAMATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL N-[3-(TOSYLOXY)PROPYL]CARBAMATE(80909-96-2)
• EPA Substance Registry System: TERT-BUTYL N-[3-(TOSYLOXY)PROPYL]CARBAMATE(80909-96-2)

Safety Data

• Hazardous Substances Data: 80909-96-2(Hazardous Substances Data)

Upstream product

• 58885-58-8 N-tert-butoxycarbonyl-3-aminopropanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 41840-28-2 S-tert-butoxycarbonyl-4,6-dimethyl-2-mercaptopyrimidine 
• 156-87-6 propan-1-ol-3-amine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 34619-03-9 tert-butyldicarbonate 

Downstream Products

• 955359-92-9 1,1-dimethylethyl (3-{4-[4-[(4-chlorophenyl)methyl]-1-oxo-2(1H)-phthalazinyl]hexahydro-1H-azepin-1-yl}propyl)carbamate 
• 913642-21-4 1,1-dimethylethyl [3-({3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-4-(3-hydroxy-3-methyl-1-butyn-1-yl)-1H-imidazo[4,5-c]pyridin-6-yl]phenyl}oxy)propyl]carbamate 
• 1085928-20-6 tert-butyl (3-(4-(2-methoxyphenyl)piperazin-1-yl)propyl)carbamate 
• 1426687-03-7 tert-butyl (3-(((4S)-6-(4-chlorophenyl)-4-(2-(ethylamino)-2-oxoethyl)-1-methyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepin-8-yl)oxy)propyl)carbamate 
• 129392-84-3 tert-butyl N-(3-azidopropyl)carbamate 

Relevant articles and documents

COMPOUNDS AND USES THEREOF

The present disclosure features compounds useful for the treatment of BAF complex-related disorders.

SMARCA DEGRADERS AND USES THEREOF

The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same for the modulation of one or more SWI/SNF-related matrix associated actin dependent regulator of chromatin subfamily A (SMARCA) and/or polybromo-1 (PB-1) protein via ubiqitination and/or degradation by compounds. The compounds are bifunctional molecules that link a cereblon-binding moiety to a ligand that binds SMARCA and/or PB1 proteins.

For the treatment of tumor macrocyclic derivatives (by machine translation)

The invention discloses a method for modulating protein kinase activity, and is used for the treatment or prevention of protein kinase related disorders. Specifically, the invention relates to a method for the treatment of tumor of the macrocyclic derivatives, which belongs to the regulating Anaplastic lymphoma kinase (ALK) active compound, and provides the preparation method of the compound, and the compound used for the treatment or prevention of diseases associated with the ALK pharmaceutical use. (by machine translation)