809274-63-3

Basic information

• Product Name: Quinoline, 3-iodo-4-phenyl-
• CAS NO: 809274-63-3
• Molecular Formula: C15H10IN
• Molecular Weight: 331.156
• Mol File: 809274-63-3.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Quinoline, 3-iodo-4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Quinoline, 3-iodo-4-phenyl-(809274-63-3)
• EPA Substance Registry System: Quinoline, 3-iodo-4-phenyl-(809274-63-3)

Safety Data

• Hazardous Substances Data: 809274-63-3(Hazardous Substances Data)

Upstream product

• 14465-74-8 N-phenyl-N-prop-2-ynylamine 
• 809274-73-5 N-phenyl-N-(3-phenyl-2-propyn-1-yl)methanesulfonamide 
• 1203703-02-9 4-methyl-N-phenyl-N-(3-phenylprop-2-yn-1-yl)benzenesulfonamide 
• 305837-95-0 4-methyl-N-(3-phenylprop-2-yn-1-yl)benzenesulfonamide 
• 66003-76-7 Diphenyliodonium triflate 
• 62-53-3 aniline 
• 1217436-49-1 N-(1-benzyl-3-phenylprop-2-ynyl)aniline 
• 1197-22-4 N-phenylmethanesulfonamide 
• 1504-58-1 3-Phenyl-2-propyn-1-ol 
• 591-50-4 iodobenzene 
• 809274-74-6 3-iodo-1-methanesulfonyl-4-phenyl-1,2-dihydroquinoline 
• 121194-51-2 N-(3-phenylprop-2-ynyl)benzenamine 

Downstream Products

• 17282-99-4 3,4-diphenylquinoline 
• 605-03-8 4-phenylquinoline 
• 206-55-3 indeno[1,2,3-de]quinoline 

Relevant articles and documents

Synthesis of Multibromo-Substituted Quinolines by NBS-Mediated Cascade Electrophilic Bromination/Cyclization of N -(3-Phenylprop-2-ynyl)anilines

A new and convenient protocol is presented here for the synthesis of 3,6,8-tribromoquinolines via cascade cyclization of N -(3-phenylprop-2-ynyl)anilines employing N -bromosuccinimide as an electrophile. The metal-free process is carried out under mild conditions and is compatible with a variety of substituents. The Sonogashira coupling reaction regioselectively occurs at position C-6 of the obtained products.

Hypervalent iodine compound containing heterocyclic ring as well as preparation method and application thereof

The invention discloses a hypervalent iodine compound containing a heterocyclic ring as well as a preparation method and application thereof. A structure of the compound is shown as a formula (I): theformula (I) is shown in the description, wherein R is selected from hydrogen, halogen, alkyl, alkoxy, halogenated alkyl, halogenated alkoxy, nitryl, cyano, hydroxyl or -COOR'; R' is alkyl or halogenated alkyl; and Het is substituted or non-substituted 1,4-benzopyranone, substituted or non-substituted quinolone, substituted or non-substituted isoquinoline, substituted or non-substituted thiobenzopyranone, substituted or non-substituted coumarin and substituted or non-substituted oxepin. The compound disclosed by the invention is novel in structure and is the hypervalent iodine compound containing the heterocyclic ring; the hypervalent iodine compound is stable in structure and simple in preparation method; and meanwhile, the hypervalent iodine compound has a very good inhibition effect onML-1 and MOLM-13 cells and has an extremely great application prospect on prevention and/or treatment effect on leukemia.

Synthesis of quinolines by electrophilic cyclization of n-(2- alkynyl)anilines: 3-iodo-4-phenylquinoline

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