813432-31-4Relevant articles and documents
New constrained "molecular tongs" designed to dissociate HIV-1 protease dimer
Merabet, Naima,Dumond, Julien,Collinet, Bruno,Van Baelinghem, Laurence,Boggetto, Nicole,Ongeri, Sandrine,Ressad, Fariza,Reboud-Ravaux, Michèle,Sicsic, Sames
, p. 6392 - 6400 (2007/10/03)
New "molecular tongs" based on naphthalene and quinoline scaffolds linked to two peptidic strands were synthesized. They were designed to prevent dimerization of HIV-1 protease by targeting the antiparallel β-sheet involving N- and C-termini of each monom