827603-84-9

Basic information

• Product Name: 2-Thiazolidinethione, 3-[[(R)-(diphenylmethyl)sulfinyl]acetyl]-4-phenyl-, (4R)-
• CAS NO: 827603-84-9
• Molecular Formula: C24H21NO2S3
• Molecular Weight: 451.634
• Mol File: 827603-84-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 134-136 °C (decomp)
• Boiling Point: 670.3±65.0 °C(Predicted)
• Density: 1.40±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 2-Thiazolidinethione, 3-[[(R)-(diphenylmethyl)sulfinyl]acetyl]-4-phenyl-, (4R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Thiazolidinethione, 3-[[(R)-(diphenylmethyl)sulfinyl]acetyl]-4-phenyl-, (4R)-(827603-84-9)
• EPA Substance Registry System: 2-Thiazolidinethione, 3-[[(R)-(diphenylmethyl)sulfinyl]acetyl]-4-phenyl-, (4R)-(827603-84-9)

Safety Data

• Hazardous Substances Data: 827603-84-9(Hazardous Substances Data)

Upstream product

• 110199-18-3 (4R)-4-phenyl-1,3-thiazolidine-2-thione 
• 63547-24-0 modafinil acid 

Downstream Products

• 112111-45-2 (R)-Modafinil acid 
• 112111-43-0 Nuvigil 

Relevant articles and documents

Synthesis and determination of the absolute stereochemistry of the enantiomers of adrafinil and modafinil

Both enantiomers of modafinil, adrafinil, modafinic acid and ethyl modafinate were prepared from the diastereomers formed by reacting racemic β-sulfinyl carboxylic acid with (4R)-phenyl-thiazolidinethione. The absolute stereochemistry of the sulfoxide group was confirmed via X-ray analysis of one of the thiazolidinethione diastereomers.