84468-53-1

Basic information

• Product Name: 2-ISOPROPYL-PIPERAZINE
• Synonyms: 2-ISOPROPYL-PIPERAZINE;2-ISOPROPYLPIPERAZINE-2HCl;2-Isopropylpiperazine dihydrochloride
• CAS NO: 84468-53-1
• Molecular Formula: C₇H₁₆N₂
• Molecular Weight: 128.22
• Mol File: 84468-53-1.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 184.1 °C at 760 mmHg
• Flash Point: 64.6 °C
• Appearance: /
• Density: 0.851 g/cm³
• PKA: 9.21±0.40(Predicted)
• CAS DataBase Reference: 2-ISOPROPYL-PIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ISOPROPYL-PIPERAZINE(84468-53-1)
• EPA Substance Registry System: 2-ISOPROPYL-PIPERAZINE(84468-53-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26
• HazardClass: IRRITANT
• Hazardous Substances Data: 84468-53-1(Hazardous Substances Data)

Usage

General Description

2-isopropyl-piperazine is a chemical compound that belongs to the class of organic compounds known as piperazines. Piperazines are compounds containing a piperazine ring, which is a six-member saturated ring with two nitrogen atoms at opposite positions. The "2-isopropyl" part refers to the presence of an isopropyl group, a branched chain of carbon atoms, attached to the second carbon in the ring. 2-ISOPROPYL-PIPERAZINE is used in the synthesis of various pharmaceuticals and can also act as a precursor to other chemicals. Its exact properties, such as its boiling point, melting point, or potential hazards, can depend on the specific conditions under which it is prepared or used.

Upstream product

• 16944-60-8 3-isopropyl-piperazine-2,5-dione 
• 29460-90-0 2-(1-methylethyl)pyrazine 
• 16944-60-8 (2S)-isopropylpiperazine-3,6-dione 
• 2421-61-6 N-benzyloxycarbonylvalylglycine methyl ester 
• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 
• 324748-62-1 (S)-1-benzyl-3-isopropylpiperazine 
• 674792-05-3 (S)-tert-butyl 2-isopropylpiperazine-1-carboxylate 

Downstream Products

• 133181-65-4 (S)-1,4-di-(benzyloxycarbonyl)-2-isopropylpiperazine 
• 502493-89-2 C₂₀H₂₆N₂ 
• 13754-38-6 N-Benzoylpiperazine 
• 1001183-94-3 C₁₄H₂₀FN₃O 
• 1010741-50-0 C₁₆H₂₃N₅ 
• 1001184-89-9 N-(4-chlorophenyl)-3-isopropylpiperazine-1-carboxamide 
• 1529801-17-9 benzyl 3-isopropylpiperazine-1-carboxylate 
• 1529801-18-0 benzyl-4-(N'-cyano-N-o-tolylcarbamimidoyl)-3-isopropylpiperazine-1-carboxylate 
• 1529801-16-8 N'-cyano-2-isopropyl-N-(o-tolyl)piperazine-1-carboximidamide 

Relevant articles and documents

CYANOGUANIDINES AND THEIR USE AS ANTIVIRAL AGENTS

This disclosure relates to: (a) compounds and salts thereof that, inter alia, inhibit RSV infection and/or replication; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; (e) methods of use of such compounds, salts, and compositions; and (f) kits comprising such compounds, salts, and compositions.

Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma

The discovery of a pyrrolopyrimidine class of LIM-kinase 2 (LIMK2) inhibitors is reported. These LIMK2 inhibitors show good potency in enzymatic and cellular assays and good selectivity against ROCK. After topical dosing to the eye in a steroid induced mouse model of ocular hypertension, the compounds reduce intraocular pressure to baseline levels. The compounds also increase outflow facility in a pig eye perfusion assay. These results suggest LIMK2 may be an effective target for treating ocular hypertension and associated glaucoma.

17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 INHIBITORS FOR THE TREATMENT OF ANDROGEN DEPENDENT DISEASES

In its many embodiments, the present invention provides a novel class of compounds as inhibitors of type 3 17?-hydroxysteroid dehydrogenase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of