849767-19-7

Basic information

• Product Name: tert-butyl 4-hydroxy-3-(hydroxymethyl)piperidine-1-carboxylate
• Synonyms: tert-butyl 4-hydroxy-3-(hydroxymethyl)piperidine-1-carboxylate
• CAS NO: 849767-19-7
• Molecular Formula: C11H21NO4
• Molecular Weight: 231.28874
• Mol File: 849767-19-7.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: tert-butyl 4-hydroxy-3-(hydroxymethyl)piperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-hydroxy-3-(hydroxymethyl)piperidine-1-carboxylate(849767-19-7)
• EPA Substance Registry System: tert-butyl 4-hydroxy-3-(hydroxymethyl)piperidine-1-carboxylate(849767-19-7)

Safety Data

• Hazardous Substances Data: 849767-19-7(Hazardous Substances Data)

Usage

General Description

Tert-butyl 4-hydroxy-3-(hydroxymethyl)piperidine-1-carboxylate is a chemical compound with the molecular formula C13H23NO4. It is a derivative of piperidine and is often used as a pharmaceutical intermediate in the synthesis of various medications. The compound is a white solid that is soluble in organic solvents and is stable under normal conditions. It is commonly used in the pharmaceutical industry for its ability to modify the properties of certain drugs, such as enhancing their stability or bioavailability. Additionally, it has potential applications in the field of medicinal chemistry for the development of new pharmaceutical compounds.

Upstream product

• 161491-24-3 methyl 1-tert-butoxycarbonyl-4-oxo-3-piperidinecarboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 71486-53-8 methyl 4-oxo-3-piperidinecarboxylate hydrochloride 
• 1454-53-1 ethyl 1-benzyl-4-oxopiperidine-3-carboxylate hydrochloride 
• 98977-34-5 1-tert-butyl 3-ethyl 4-oxopiperidine-1,3-dicarboxylate 

Downstream Products

• 849767-21-1 tert-butyl 3-[[tert-butyl(dimethyl)silyl]oxymethyl]-4-oxo-piperidine-1-carboxylate 
• 1331775-94-0 4-[6-butyl-5-(4-cyclohexyloxyphenyl)pyridazin-3-yloxy]-3-methoxymethoxymethylpiperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

MITOCHONDRIAL INHIBITORS FOR THE TREATMENT OF PROLIFERATION DISORDERS

The invention provides compounds of formula I or pharmaceutically acceptable salt, solvate or hydrate thereof (I) wherein ring A represents group A-I or A- II (A-I, A-II) A1, A2, A3, A4 represent independently C(R4aa) or N, wherein no more than one of A1, A2, A3, and A4 represents N; A5 represents C(R4b) or N; B1, B2, B3 and B4 represent independently C(R3) or N, wherein no more than two of B1, B2, B3 and B4 represent N; n is 1 or 2; and R1, R2, R3, R4a and R4aa and R4b are as defined in the claims, as well as methods of using the compounds to treat proliferation diseases, in particular cancer.

FUSED PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS

The invention relates to fused piperidine amides useful as inhibitors of ion channels for the treatment of pain. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

PHENYL-HETEROARYL DERIVATIVES AND METHODS OF USE THEREOF

The present invention provides phenyl-heteroaryl derivatives of Formula (I) and pharmaceutically acceptable salts thereof. These compounds are useful in the treatment of RAGE-mediated diseases such as Alzheimer's Disease. The present invention further relates to methods for the preparation of compounds of Formula (I) and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising such compounds, and the use of such compounds and/or pharmaceutical compositions in treating RAGE-mediated diseases.