849767-21-1

Basic information

• Product Name: 1-BOC-3-[(1,1-DIMETHYLETHYL)DIMETHYLSILYLOXYMETHYL]-PIPERIDIN-4-ONE
• Synonyms: 1-BOC-3-[(1,1-DIMETHYLETHYL)DIMETHYLSILYLOXYMETHYL]-PIPERIDIN-4-ONE;1-Piperidinecarboxylicacid,3-[[[(1,1-diMethylethyl)diMethylsilyl]oxy]Methyl]-4-oxo-,1,1-diMethylethylester;tert-Butyl 3-(((tert-butyldiMethylsilyl)oxy)Methyl)-4-oxopiperidine-1-carboxylate;tert-Butyl 3-(((tert-butyldimethylsilyl)
• CAS NO: 849767-21-1
• Molecular Formula: C₁₇H₃₃NO₄Si
• Molecular Weight: 343.53
• Mol File: 849767-21-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-BOC-3-[(1,1-DIMETHYLETHYL)DIMETHYLSILYLOXYMETHYL]-PIPERIDIN-4-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BOC-3-[(1,1-DIMETHYLETHYL)DIMETHYLSILYLOXYMETHYL]-PIPERIDIN-4-ONE(849767-21-1)
• EPA Substance Registry System: 1-BOC-3-[(1,1-DIMETHYLETHYL)DIMETHYLSILYLOXYMETHYL]-PIPERIDIN-4-ONE(849767-21-1)

Safety Data

• Hazardous Substances Data: 849767-21-1(Hazardous Substances Data)

Usage

General Description

1-BOC-3-[(1,1-Dimethylethyl)dimethylsilyloxy methyl]-piperidin-4-one, also known as Boc-piperidone, is a chemical compound commonly used in organic synthesis and pharmaceutical research. It is a derivative of piperidone, a heterocyclic organic compound, and contains a tertiary butyl carbamate (Boc) protecting group, as well as a silyl ether functional group. 1-BOC-3-[(1,1-DIMETHYLETHYL)DIMETHYLSILYLOXYMETHYL]-PIPERIDIN-4-ONE is often used as a key intermediate in the synthesis of various drugs and pharmaceutical compounds due to its stability and reactivity. Boc-piperidone is also used in the synthesis of other important chemicals, such as ligands and biologically active molecules, making it a valuable reagent in chemical research and development.

Upstream product

• 849767-20-0 tert-butyl 3-[[tert-butyl(dimethyl)silyl]oxymethyl]-4-hydroxy-piperidine-1-carboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 71486-53-8 methyl 4-oxo-3-piperidinecarboxylate hydrochloride 
• 161491-24-3 methyl 1-tert-butoxycarbonyl-4-oxo-3-piperidinecarboxylate 
• 849767-19-7 tert-butyl 4-hydroxy-3-(hydroxymethyl)piperidine-1-carboxylate 
• 98977-34-5 1-tert-butyl 3-ethyl 4-oxopiperidine-1,3-dicarboxylate 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Relevant articles and documents

CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF

Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of chemokine receptor activity.

FUSED PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS

The invention relates to fused piperidine amides useful as inhibitors of ion channels for the treatment of pain. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

Piperdine derivatives useful as CCR3 antagonists

The use of CCR3 antagonists of the formula I or a pharmaceutically acceptable salt thereof for the treatment of asthma is disclosed, as well as novel compounds of the formula II, pharmaceutical compositions comprising them, and their use in the treatment