851916-39-7

Basic information

• Product Name: (1S,4S)-4-(2,5-diMethyl-1H-pyrrol-1-yl)-1-(propan-2-yl)cyclopent-2-ene-1-carboxylic acid
• Synonyms: (1S,4S)-4-(2,5-diMethyl-1H-pyrrol-1-yl)-1-(propan-2-yl)cyclopent-2-ene-1-carboxylic acid;(1S,4S)-4-(2,5-diMethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-enecarboxylic acid;YXAJQLUEPZZFJT-HIFRSBDPSA-N
• CAS NO: 851916-39-7
• Molecular Formula: C15H21NO2
• Molecular Weight: 247.33274
• Mol File: 851916-39-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (1S,4S)-4-(2,5-diMethyl-1H-pyrrol-1-yl)-1-(propan-2-yl)cyclopent-2-ene-1-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,4S)-4-(2,5-diMethyl-1H-pyrrol-1-yl)-1-(propan-2-yl)cyclopent-2-ene-1-carboxylic acid(851916-39-7)
• EPA Substance Registry System: (1S,4S)-4-(2,5-diMethyl-1H-pyrrol-1-yl)-1-(propan-2-yl)cyclopent-2-ene-1-carboxylic acid(851916-39-7)

Safety Data

• Hazardous Substances Data: 851916-39-7(Hazardous Substances Data)

Usage

General Description

The chemical (1S,4S)-4-(2,5-diMethyl-1H-pyrrol-1-yl)-1-(propan-2-yl)cyclopent-2-ene-1-carboxylic acid is a complex organic compound with a specific molecular structure. It belongs to the class of carboxylic acids and contains a cyclopentene ring with a substituted pyrrole group. The compound is asymmetric, with a stereochemistry denoted by the (1S,4S) prefix. It is also known as a chiral molecule, meaning it has non-superimposable mirror images. The chemical's unique structure and properties make it potentially useful in various pharmaceutical, chemical, and biological applications, prompting further research and potential development for specific uses.

Upstream product

• 851916-45-5 methyl (1S,4S)-4-(2,5-dimethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-ene-1-carboxylate 

Relevant articles and documents

AMINOCYCLOPENTYL PYRIDOPYRAZINONE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

Compounds of Formula I and Formula II (wherein A, E, j, k, m, n, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R15, R16, R17, R18, R19, R24, R25, R26, R27, R28, R29, R30, R31, R32, R33, R34, X, Y and Z are as defined herein) which are modulators of chemokine receptor activity and are useful in the prevention or treatment of certain inflammatory and immunoregulatory disorders and diseases, allergic diseases, atopic conditions including allergic rhinitis, dermatitis, conjunctivitis, and asthma, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which chemokine receptors are involved.

PROCESS FOR THE PREPARATION OF CCR-2 ANTAGONIST

The present invention provides an efficient synthesis for the preparation of ((1R,3S)-3-isopropyl-3- {[3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]carbonyl} cyclopentyl)[(3S,4S)-3-m ethoxytetrahydro- 2H-pyran-4-yl]amine and its succinate sal