851916-45-5

Basic information

• Product Name: (1S,4S)-Methyl 4-(2,5-diMethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-enecarboxylate
• Synonyms: (1S,4S)-Methyl 4-(2,5-diMethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-enecarboxylate;methyl (1S,4S)-4-(2,5-dimethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-ene-1-carboxylate;ZOOQRHCXWMZGDG-ZBFHGGJFSA-N
• CAS NO: 851916-45-5
• Molecular Formula: C16H23NO2
• Molecular Weight: 261.35932
• Mol File: 851916-45-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 355.0±42.0 °C(Predicted)
• Appearance: /
• Density: 1.05±0.1 g/cm3(Predicted)
• PKA: -1.33±0.40(Predicted)
• CAS DataBase Reference: (1S,4S)-Methyl 4-(2,5-diMethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-enecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,4S)-Methyl 4-(2,5-diMethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-enecarboxylate(851916-45-5)
• EPA Substance Registry System: (1S,4S)-Methyl 4-(2,5-diMethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-enecarboxylate(851916-45-5)

Safety Data

• Hazardous Substances Data: 851916-45-5(Hazardous Substances Data)

Usage

Description

(1S,4S)-methyl 4-(2,5-dimethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-enecarboxylate is a complex carboxylate ester chemical compound characterized by a cyclopentene ring with an isopropyl group and a methyl ester group. It also features a pyrrole ring with two methyl substituents, indicating its potential for interaction with biological systems. This intricate structure suggests its use in pharmaceutical or research settings, possibly for medicinal purposes or in the development of new drugs or therapies.

Uses

Used in Pharmaceutical Industry:
(1S,4S)-methyl 4-(2,5-dimethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-enecarboxylate is used as a pharmaceutical compound for its potential to interact with biological systems due to its complex structure. It may contribute to the development of new drugs or therapies, particularly in areas where its specific interactions can be leveraged for medicinal benefits.
Used in Research Settings:
In research, (1S,4S)-methyl 4-(2,5-dimethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-enecarboxylate serves as a subject of study for understanding its interactions with biological systems. This can lead to insights into its potential applications in medicine, drug development, or as a tool in biochemical and pharmacological research.

Upstream product

• 75-30-9 2-iodo-propane 
• 67-56-1 methanol 
• 862121-08-2 C₁₆H₂₃NO₄S 
• 851916-44-4 (1R,4S)-methyl 4-(2,5-dimethyl-1H-pyrrol-1-yl)cyclopent-2-enecarboxylate 

Downstream Products

• 851916-39-7 (1S,4S)-4-(2,5-dimethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-ene-1-carboxylic acid 

Relevant articles and documents

AMINOCYCLOPENTYL PYRIDOPYRAZINONE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

Compounds of Formula I and Formula II (wherein A, E, j, k, m, n, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R15, R16, R17, R18, R19, R24, R25, R26, R27, R28, R29, R30, R31, R32, R33, R34, X, Y and Z are as defined herein) which are modulators of chemokine receptor activity and are useful in the prevention or treatment of certain inflammatory and immunoregulatory disorders and diseases, allergic diseases, atopic conditions including allergic rhinitis, dermatitis, conjunctivitis, and asthma, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which chemokine receptors are involved.

CCR-2 ANTAGONIST SALT

The present invention provides an efficient synthesis for the preparation of ((1R,3S)-3-isopropyl-3-{[3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]carbonyl}cyclopentyl)[(3S,4S)-3-m ethoxytetrahydro-2H-pyran-4-yl]amine and its succinate salt.