85460-26-0Relevant articles and documents
Knoevenagel condensation catalyzed by novel Nmm-based ionic liquids in water
Xu, Hao,Pan, Liyang,Fang, Xiaomin,Liu, Baoying,Zhang, Wenkai,Lu, Minghua,Xu, Yuanqing,Ding, Tao,Chang, Haibo
supporting information, p. 2360 - 2365 (2017/05/29)
A series of novel N-methyl morpholine (Nmm) based ionic liquids with 1,2-propanediol group were synthesized and used as catalysts for Knoevenagel condensation at room temperature in water. Under the effect of the catalyst, various aldehydes or aliphatic ketones could react with a wide range of activated methylene compounds well, including malononitrile, alkyl cyanoacetate, cyanoacetamide, β-diketone, barbituric acid, 2-arylacetonitrile and thiazolidinedione. Furthermore, most of the products could be separated just by filtrating and washing with water. Additionally, the catalyst is recyclable and applicable for the large-scale synthesis.
Knoevenagel condensation reaction using ionic liquid [ADPQ][CF3SO3] as green and reusable catalyst
Gao, Xiaochong,Gao, Can,Gao, Ruichang
, p. 2145 - 2148 (2015/11/28)
Knoevenagel condensation reaction of aromatic aldehydes with some active methylene compounds proceeded efficiently without solvent using ionic liquids as catalyst. The experimental results show that these ionic liquids have good catalytic activities to th
UNCATALYZED KNOEVENAGEL CONDENSATION OF 2-CYANOMETHYLBENZOTHIAZOLE WITH AROMATIC ALDEHYDES. PREPARATION OF 3-ARYL-2-(2-BENZOTHIAZOLYL)-ACRYLONITRILES AND 3-(2-BENZOTHIAZOLYL)-COUMARIN IMINES
Dryanska, Veneta
, p. 325 - 329 (2007/10/02)
A series of 3-aryl-2-(2-benzothiazolyl)-acrylonitriles (3a-n) and 3-(2-benzothiazolyl)-coumarin imines (5a-f) are prepared in good to high yields by refluxing solutions of 2-cyanomethylbenzothiazole (1) and aromatic aldehydes (2, 4) in ethanol. Key words: