56278-50-3 Usage
Description
Benzothiazole-2-acetonitrile, also known as 2-Benzothiazoleacetonitrile, is an organic compound that serves as a versatile building block in the synthesis of various chemical compounds. It is characterized by its benzothiazole ring structure and an acetonitrile functional group, which contributes to its reactivity and potential applications in different industries.
Uses
Used in Organic Synthesis:
Benzothiazole-2-acetonitrile is used as a synthetic intermediate for the preparation of various organic compounds. Its unique structure allows it to be a valuable component in the synthesis of complex molecules.
Used in Pharmaceuticals:
In the pharmaceutical industry, Benzothiazole-2-acetonitrile is used as a key building block for the development of new drugs. Its reactivity and structural properties make it suitable for the synthesis of bioactive molecules with potential therapeutic applications.
Used in Agrochemicals:
Benzothiazole-2-acetonitrile is also utilized in the agrochemical industry for the synthesis of various agrochemical products. Its incorporation into these products can enhance their effectiveness and contribute to improved agricultural practices.
Used in Dye Stuffs:
In the dyestuffs industry, Benzothiazole-2-acetonitrile is employed as a starting material for the production of dyes and pigments. Its chemical properties enable the creation of a wide range of colors and hues, making it a valuable asset in the development of new dyes.
Used in the Preparation of 3-aryl-1-[(E)-cyanomethylidene]-1H-pyrido[2,1-b]benzothiazole-4-carbonitriles:
Benzothiazole-2-acetonitrile is used as a reactant in the synthesis of 3-aryl-1-[(E)-cyanomethylidene]-1H-pyrido[2,1-b]benzothiazole-4-carbonitriles. This application is achieved through its reaction with 6-aryl-4-methylsulfanyl-2-oxo-2H-pyran-3-carbonitrile, showcasing its versatility in chemical reactions.
Used in the Synthesis of Pyrrolones:
Benzothiazole-2-acetonitrile may be employed in the preparation of pyrrolones, which are important intermediates in the synthesis of 1-acyl-3-aryl-3H-pyrrolo[2′,3′:4,5]pyrimido[6,1-b]benzothiazol-6-ium-2-olates. These complex molecules have potential applications in various fields, further highlighting the utility of Benzothiazole-2-acetonitrile as a synthetic building block.
Check Digit Verification of cas no
The CAS Registry Mumber 56278-50-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,2,7 and 8 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 56278-50:
(7*5)+(6*6)+(5*2)+(4*7)+(3*8)+(2*5)+(1*0)=143
143 % 10 = 3
So 56278-50-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H6N2S.ClH/c10-6-5-9-11-7-3-1-2-4-8(7)12-9;/h1-4H,5H2;1H
56278-50-3Relevant articles and documents
Benzimidazole-based turn-on fluorescence probe developed for highly specific and ultrasensitive detection of hypochlorite ions in living cells
Yang, Yi,Cheng, Siyao,Dong, Wei
, p. 1377 - 1384 (2021)
Hypochlorite (ClO?), as one of the active oxygen species (ROS), plays an essential role in the cellular defence system and organism immunity. In this paper, we successfully synthesized a new ‘turn-on’ fluorescent probe BMF based on benzimidazole and characterized it by spectroscopic methods. The designed probe can quickly respond to ClO? with the obvious colour change from pink to colourless. Notably, the probe BMF exhibited almost no fluorescence, but showed strong fluorescence after adding ClO?, including an excellent fluorescence turn-on effect. The fluorescence turn-on phenomenon of BMF was attributed to the strong oxidation of ClO?, which severed the connecting double bond and disrupted the intramolecular charge transfer (ICT) system, plus light-induced electron transfer effect between the fluorophore and the recognition group was discontinued. In addition, the cytotoxicity assay showed that the probe had lower cytotoxicity. Based on these advantages, we demonstrated that probe BMF might be a good candidate for detecting ClO? in biological systems.
Palladium(0)-catalyzed Synthesis of 2-Alkylbenzothiazoles by a Novel Thiation of 1-Amino-2-iodoarenes with Thioamides
Takagi, Kentaro,Iwachido, Tadashi,Hayama, Naomi
, p. 839 - 840 (2007/10/02)
Pd(0) catalyzed the reaction of 1-amino-2-iodoarenes with thioamides giving rise to 2-XCH2-substituted benzothiazoles (X=H, CH3, OCH3, and CN) directly.
