874341-58-9

Basic information

• Product Name: Cyclopropanecarboxylic acid, 1-nitro-2-phenyl-, methyl ester, (1R,2S)-
• CAS NO: 874341-58-9
• Molecular Formula: C11H11NO4
• Molecular Weight: 221.213
• Mol File: 874341-58-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Cyclopropanecarboxylic acid, 1-nitro-2-phenyl-, methyl ester, (1R,2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopropanecarboxylic acid, 1-nitro-2-phenyl-, methyl ester, (1R,2S)-(874341-58-9)
• EPA Substance Registry System: Cyclopropanecarboxylic acid, 1-nitro-2-phenyl-, methyl ester, (1R,2S)-(874341-58-9)

Safety Data

• Hazardous Substances Data: 874341-58-9(Hazardous Substances Data)

Upstream product

• 100-42-5 styrene 
• 2483-57-0 methyl 2-nitroacetate 

Downstream Products

• 1036637-41-8 methyl (4R)-4-(2,3-dihydro-1H-indol-1-yl)-2-nitro-4-phenylbutanoate 
• 1036637-31-6 methyl 5-phenyl-4,5-dihydroisoxazole-3-carboxylate 2-oxide 
• 1047675-87-5 methyl (4R)-4-(2-methylphenoxy)-2-nitro-4-phenylbutanoate 
• 1047675-89-7 methyl (4R)-4-(2-bromophenoxy)-2-nitro-4-phenylbutanoate 
• 95-62-5 (1R,2S)-1-amino-2-phenylcyclopropane 
• 123806-63-3 methyl (1R,2S)-1-amino-2-phenylcyclopropanecarboxylate 
• 874341-82-9 [(1S,2R)-2-nitrocyclopropyl]benzene 

Relevant articles and documents

Expedient synthesis of cyclopropane α-amino acids by the catalytic asymmetric cyclopropanation of alkenes using iodonium ylides derived from methyl nitroacetate

A highly enantioselective (up to 97.5% ee) and diastereoselective (95:5 dr trans/cis) Cu(I)-catalyzed cyclopropanation of alkenes using phenyliodonium ylide generated in situ from iodosobenzene and methyl nitroacetate is reported. The cyclopropanation took place with high enantioselectivity for a wide range of alkenes, and the reaction was performed at room temperature. 1-Nitrocyclopropyl esters are versatile building blocks to access the corresponding cyclopropane amino esters and aminocyclopropanes in two and three steps, respectively, from commercially available products. Copyright