874341-82-9

Basic information

• Product Name: Benzene, [(1S,2R)-2-nitrocyclopropyl]-
• CAS NO: 874341-82-9
• Molecular Formula: C9H9NO2
• Molecular Weight: 163.176
• Mol File: 874341-82-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzene, [(1S,2R)-2-nitrocyclopropyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, [(1S,2R)-2-nitrocyclopropyl]-(874341-82-9)
• EPA Substance Registry System: Benzene, [(1S,2R)-2-nitrocyclopropyl]-(874341-82-9)

Safety Data

• Hazardous Substances Data: 874341-82-9(Hazardous Substances Data)

Upstream product

• 100-42-5 styrene 
• 1036637-32-7 methyl (1S,2R)-1-nitro-2-phenylcyclopropanecarboxylate 
• 874341-58-9 methyl (1R,2S)-1-nitro-2-phenylcyclopropanecarboxylate 

Downstream Products

• 95-62-5 (1R,2S)-1-amino-2-phenylcyclopropane 
• 54-97-7 1-amino-2-phenylcyclopropane 
• 3721-28-6 (1S,2R)-tranylcypromine 
• 50584-02-6 trans-2-Benzamido-1-phenyl-cyclopropan 

Relevant articles and documents

Catalytic asymmetric synthesis of nitrocyclopropane carboxylates

A Cu(I)-catalyzed asymmetric cyclopropanation of alkenes with an iodonium ylide has been developed. The copper source, hypervalent iodine source, solvent, and additives all have a significant effect on the yields and enantioselectivities. High enantioselectivity (up to 99:1 er) and diastereoselectivity (95:5 dr trans/cis) were achieved for a wide range of alkenes. Conditions were developed to convert the trans products to the cis isomers. In addition, 1-nitrocyclopropyl carboxylates were transformed into the corresponding substituted cyclopropane amino acids and aminocyclopropanes. Moreover, a comparative study between Zn- and In-mediated reduction reactions of the nitro group in these compounds with regards to the er erosion in the process is also documented.