87484-83-1

Basic information

• Product Name: (2-AMINO-2-METHYL-PROPYL)-UREA
• Synonyms: (2-AMINO-2-METHYL-PROPYL)-UREA;Urea, N-(2-amino-2-methylpropyl)-
• CAS NO: 87484-83-1
• Molecular Formula: C₅H₁₃N₃O
• Molecular Weight: 131.18
• Mol File: 87484-83-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 224.7°C at 760 mmHg
• Flash Point: 89.7°C
• Appearance: /
• Density: 1.054g/cm³
• Vapor Pressure: 0.0899mmHg at 25°C
• Refractive Index: 1.488
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (2-AMINO-2-METHYL-PROPYL)-UREA(CAS DataBase Reference)
• NIST Chemistry Reference: (2-AMINO-2-METHYL-PROPYL)-UREA(87484-83-1)
• EPA Substance Registry System: (2-AMINO-2-METHYL-PROPYL)-UREA(87484-83-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 87484-83-1(Hazardous Substances Data)

Usage

General Description

(2-Amino-2-methyl-propyl)-urea, also known as amitrole, is a chemical compound with the molecular formula C4H10N2O. It is widely used as a herbicide to control grass and weed growth in various agricultural settings. Amitrole works by inhibiting the enzyme system responsible for the biosynthesis of amino acids in plants, leading to their eventual death. It is a white crystalline solid that is soluble in water and has low volatility. Due to its potential environmental and health impacts, the use of amitrole has been restricted or banned in some countries. Additionally, exposure to amitrole is associated with potential health hazards, including skin and eye irritation, and it may also be harmful if ingested or inhaled.

InChI:InChI=1/C5H13N3O/c1-5(2,7)3-8-4(6)9/h3,7H2,1-2H3,(H3,6,8,9)

Upstream product

• 57-13-6 urea 
• 811-93-8 1,1-dimethylethylenediamine 

Downstream Products

• 85850-29-9 2-[3-(1,1-Dimethyl-2-ureido-ethylamino)-2-hydroxy-propoxy]-benzoic acid ethyl ester 
• 144256-24-6 3-{4-[3-(1,1-Dimethyl-2-ureido-ethylamino)-2-hydroxy-propoxy]-phenyl}-propionic acid methyl ester 
• 144256-22-4 (E)-3-{4-[3-(1,1-Dimethyl-2-ureido-ethylamino)-2-hydroxy-propoxy]-phenyl}-acrylic acid methyl ester 
• 144256-23-5 3-{4-[3-(1,1-Dimethyl-2-ureido-ethylamino)-2-hydroxy-propoxy]-phenyl}-propionic acid 2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester 
• 87721-62-8 3-<<1,1-dimethyl-2-<(aminocarbonyl)amino>ethyl>amino>-2-hydroxypropyl 2-fluorobenzoate 
• 85864-51-3 methyl 2-[2-Hydroxy-3-[N-[1,1-dimethyl-2-(aminocarbonylamino)ethyl]amino]propoxy]benzoate 

Relevant articles and documents

2-hydroxypropylamine heteroaryl ester derivatives

The present invention relates to compounds of the general formula STR1 wherein Ar represents a substituted or unsubstituted heterocyclic group; W represents alkylene of from 1 to about 10 carbon atoms; and B represents --NR2 COR1, --NR2 CONR1 R3, --NR2 SO2 R1, NR2 SO2 NR1 R3, or --NR2 COOR1, wherein R1, R2 and R3 may be alike or different and may be hydrogen, alkyl, alkoxyalkyl cycloalkyl, alkenyl, alkynyl, aryl, heteroaryl, or aralkyl, except that R1 is not hydrogen when B is --NR2 SO2 R1 or --NR2 COOR1, or R1 and R3 may together with N form a 5 to 7 membered heterocyclic group and the pharmaceutically acceptable salts thereof. The compounds exhibit beta-adrenergic blocking activity and are also useful in the treatment of glaucoma.

Esters of thiadiazole oxypropanolaine derivatives and pharmaceutical uses

Novel compounds of the general formula STR1 wherein R1 is lower alkyl, lower cycloalkyl, lower alkenyl, lower alkynyl, lower alkyl carboxymethyl, aryl carboxymethyl, aryl, or aralkyl; A is a direct bond, lower alkylene, or lower alkenylene; x is 1 or 2, provided that when x is greater than 1, different occurrences of the STR2 group may be the same or different; Ar is heterocyclic, unsubstituted aromatic or aromatic substituted with lower alkyl, lower alkenyl, lower alkynyl, lower alkoxy, halogen, acetamido, amino, nitro, lower alkylamino, hydroxy, lower hydroxyalkyl or cyano; W is alkylene containing from 1 to about 10 carbon atoms; and B is --NR2 COR3, --NR2 CONR3 R4, --NR2 SO2 R3, --NR2 SO2 NR3 R4, or --NR2 COOR5, wherein R2, R3, R4 and R5 may be the same or different and may be hydrogen, alkyl, alkoxyalkyl, alkoxyaryl, cycloalkyl, alkenyl, alkynyl, aryl, heteroaryl, or aralkyl, except that R3 and R5 are not hydrogen when B is --NR2 SO2 R3 or --NR2 COOR5, or R3 and R4 may together with N form a 5 to 7 membered heterocyclic group; and the pharmaceutically acceptable salts thereof.