876307-10-7

Basic information

• Product Name: 1H-Indole-1-carboxylic acid, 3-[(1E)-3-oxo-3-[(4R)-2-oxo-4-phenyl-3-oxazolidinyl]-1-propenyl]-, 1,1-dimethylethyl ester
• CAS NO: 876307-10-7
• Molecular Formula: C25H24N2O5
• Molecular Weight: 432.476
• Mol File: 876307-10-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Indole-1-carboxylic acid, 3-[(1E)-3-oxo-3-[(4R)-2-oxo-4-phenyl-3-oxazolidinyl]-1-propenyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-1-carboxylic acid, 3-[(1E)-3-oxo-3-[(4R)-2-oxo-4-phenyl-3-oxazolidinyl]-1-propenyl]-, 1,1-dimethylethyl ester(876307-10-7)
• EPA Substance Registry System: 1H-Indole-1-carboxylic acid, 3-[(1E)-3-oxo-3-[(4R)-2-oxo-4-phenyl-3-oxazolidinyl]-1-propenyl]-, 1,1-dimethylethyl ester(876307-10-7)

Safety Data

• Hazardous Substances Data: 876307-10-7(Hazardous Substances Data)

Upstream product

• 3282-30-2 pivaloyl chloride 
• 359700-09-7 (E)-3-(1-(tert-butoxycarbonyl)-1H-indol-3-yl)acrylic acid 
• 1204-06-4 trans-3-indole-acrylic acid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 90319-52-1 (4R)-phenyl-2-oxazolidinone 

Relevant articles and documents

Synthesis of (2S,3S)-β-methyltryptophan

Nα-Fmoc-protected (2S,3S)-β-methyltryptophan has been synthesized by asymmetric synthesis through the aid of an oxazolidinone auxiliary. Coupling of the mixed anhydride of Nin-Boc-protected indoleacrylic acid to the oxazolidinone auxiliary was achieved by lithium bromide and N,N-dimethylpyridine (DMAP). This reaction is milder and more convenient to run than the traditional conditions using butyl lithium.