88681-04-3

Basic information

• Product Name: N-(2-chloro-4-nitrophenyl)benzenesulfonamide
• CAS NO: 88681-04-3
• Molecular Formula: C₁₂H₉ClN₂O₄S
• Molecular Weight: 312.7289
• Mol File: 88681-04-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 470.8°C at 760 mmHg
• Flash Point: 238.5°C
• Density: 1.545g/cm³
• Vapor Pressure: 4.92E-09mmHg at 25°C
• Refractive Index: 1.661
• CAS DataBase Reference: N-(2-chloro-4-nitrophenyl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-chloro-4-nitrophenyl)benzenesulfonamide(88681-04-3)
• EPA Substance Registry System: N-(2-chloro-4-nitrophenyl)benzenesulfonamide(88681-04-3)

Safety Data

• Hazardous Substances Data: 88681-04-3(Hazardous Substances Data)

Upstream product

• 21226-30-2 2-chloro-1-(benzenesulfonylamino)benzene 
• 666996-03-8 N,N-bis-benzenesulfonyl-2-chloro-4-nitro-aniline 
• 98-09-9 benzenesulfonyl chloride 
• 121-87-9 2-Chloro-4-nitroaniline 
• 88680-87-9 benzenesulfonic acid-(4-amino-2-chloro-anilide) 
• 95-51-2 o-chloroaniline 

Downstream Products

• 88680-87-9 benzenesulfonic acid-(4-amino-2-chloro-anilide) 
• 6318-10-1 1-benzenesulfonylamino-4-benzoylamino-2-chloro-benzene 

Relevant articles and documents

Antifungal activities of N-arylbenzenesulfonamides against phytopathogens and control efficacy on wheat leaf rust and cabbage club root diseases.

A set of N-arylbenzenesulfonamides with various substituents at the arylamine and benzenesulfonyl positions were prepared, and their antifungal properties were measured in vitro against such plant pathogenic fungi as Pythium ultimum, Phytophthora capsici, Rhizoctonia solani, and Botrytis cinerea. Compounds 3, 4, 8, 9, 10, 14, 16, 18, 20, 21, 24 and 27 had antifungal activity over a broad spectrum of the phytopathogenic fungi tested, where 50% of inhibition (ED50) was in the range of 3-15 microg/ml. Based on the in vitro activity, six derivatives (3, 4, 10, 18, 21 and 27) were selected and tested further for their fungicidal efficacy in vivo. The fungicidal efficacy of 10, 21 and 27 had a disease control value of over 85% at 50 microg/ml against wheat leaf rust, while that of 4 was selective against cabbage club root disease.