886980-61-6Relevant articles and documents
INHIBITORS OF NOTCH SIGNALLING PATHWAY AND USE THEREOF IN TREATMENT OF CANCERS
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Page/Page column 152, (2020/10/21)
The present invention relates to new inhibitors of Notch signalling pathway and its use in the treatment and/or prevention of cancers.
MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE
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Page/Page column 86, (2019/01/17)
Provided are IDO inhibitor compounds of Formula I and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of diseases. Formula (I):
Substituted pyridine and pyrimidine derivatives and their use in treating viral infections
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Page/Page column 148; 149; 150, (2016/09/26)
The present invention provides compounds of Formula (I): and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and prodrugs of said compounds, wherein each of R, R1, X, Y, Z, R2, R3, R4, R5, R6, R7, R8, R9, R18, R19 and n is selected independently and as defined herein. Compositions comprising such compounds are also provided. The compounds of the invention are effective as inhibitors of HCV, and are useful, alone and together with other therapeutic agents, in treating or preventing diseases or disorders such as viral infections and virus-related disorders.