889767-08-2

Basic information

• Product Name: ethyl 5-(4-chlorophenyl)-2-methyl-1-(4-sulfamoylphenyl)-1H-pyrrole-3-carboxylate
• Synonyms: ethyl 5-(4-chlorophenyl)-2-methyl-1-(4-sulfamoylphenyl)-1H-pyrrole-3-carboxylate
• CAS NO: 889767-08-2
• Molecular Weight: 418.901
• Mol File: 889767-08-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 5-(4-chlorophenyl)-2-methyl-1-(4-sulfamoylphenyl)-1H-pyrrole-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 5-(4-chlorophenyl)-2-methyl-1-(4-sulfamoylphenyl)-1H-pyrrole-3-carboxylate(889767-08-2)
• EPA Substance Registry System: ethyl 5-(4-chlorophenyl)-2-methyl-1-(4-sulfamoylphenyl)-1H-pyrrole-3-carboxylate(889767-08-2)

Safety Data

• Hazardous Substances Data: 889767-08-2(Hazardous Substances Data)

Upstream product

• 111787-82-7 2-[2-(4-chlorophenyl)-2-oxo-ethyl]-3-oxo-butyric acid ethyl ester 
• 63-74-1 sulfanilamide 

Downstream Products

• 1000280-40-9 5-(4-chloro-phenyl)-4-iodo-2-methyl-1-(4-sulfamoyl-phenyl)-1H-pyrrole-3-carboxylic acid ethyl ester 
• 1000279-69-5 A-867744 

Relevant articles and documents

Discovery of 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl) benzenesulfonamide (A-867744) as a novel positive allosteric modulator of the α7 nicotinic acetylcholine receptor

The discovery of a series of pyrrole-sulfonamides as positive allosteric modulators (PAM) of α7 nAChRs is described. Optimization of this series led to the identification of 19 (A-867744), a novel type II PAM with good potency and selectivity. Compound 19