89463-74-1

Basic information

• Product Name: 3-Pyridazinecarboxylicacid,hydrazide(7CI)
• Synonyms: 3-Pyridazinecarboxylicacid,hydrazide(7CI)
• CAS NO: 89463-74-1
• Molecular Formula: C5H6N4O
• Molecular Weight: 138.13
• Product Categories: AMIDE
• Mol File: 89463-74-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-Pyridazinecarboxylicacid,hydrazide(7CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridazinecarboxylicacid,hydrazide(7CI)(89463-74-1)
• EPA Substance Registry System: 3-Pyridazinecarboxylicacid,hydrazide(7CI)(89463-74-1)

Safety Data

• Hazardous Substances Data: 89463-74-1(Hazardous Substances Data)

Usage

General Description

3-Pyridazinecarboxylic acid, hydrazide (7CI) is a chemical compound with the molecular formula C5H5N3O and a molecular weight of 127.11 g/mol. It is a hydrazide derivative of pyridazinecarboxylic acid, consisting of a pyridazine ring with a carboxylic acid group and a hydrazide group attached to it. 3-Pyridazinecarboxylicacid,hydrazide(7CI) is used as a building block in the synthesis of various pharmaceuticals and agrochemicals. It also exhibits potential biological activities, such as antitumor, antiviral, and antifungal properties. Additionally, it has been studied for its potential as a corrosion inhibitor in industrial applications, as well as for its ability to chelate metal ions. Overall, 3-Pyridazinecarboxylic acid, hydrazide (7CI) has a range of potential applications in both the pharmaceutical and industrial sectors.

Upstream product

• 1126-10-9 ethyl 3-pyridazinecarboxylate 
• 34253-02-6 Methyl pyridazine-3-carboxylate 
• 2164-61-6 pyridazine-3-carboxylic acid 
• 1632-76-4 3-methylpyridazine 

Relevant articles and documents

Non-Porous Iron(II)-Based Sensor: Crystallographic Insights into a Cycle of Colorful Guest-Induced Topotactic Transformations

Materials capable of sensing volatile guests at room temperature by an easily monitored set of outputs are of great appeal for development as chemical sensors of small volatile organics and toxic gases. Herein the dinuclear iron(II) complex, [FeII2(L)2(CH3CN)4](BF4)4?2 CH3CN (1) [L=4-(4-methylphenyl)-3-(3-pyridazinyl)-5-pyridyl-4H-1,2,4-triazole], is shown to undergo reversible single-crystal-to-single-crystal (SCSC) transformations upon exposure to vapors of different guests: 1 (MeCN)?2 (EtOH)→3 (H2O)?1 (MeCN). Whilst 1 and 2 remain dimetallic, SCSC to 3 involves conversion to a 1D polymeric chain (due to a change in L bridging mode), which, remarkably, can undergo SCSC de-polymerization, reforming dimetallic 1. Additionally, SC-XRD studies of two ordered transient forms, 1TF3 and 2TF3, confirm that guest exchange occurs by diffusion of the new guests into the non-porous lattices as the old guests leave. These reversible SCSC events also induce color and magnetic responses. Indeed dark red 1 is spin crossover active (T1/2↓ 356 K; T1/2↑ 369 K), whilst orange 2 and yellow 3 remain high spin.

P2X7 MODULATORS

The present invention is directed to a compound of Formula (I) and to pharmaceutical compositions comprising compounds of Formula (I). Methods of making and using the compounds of Formula (I) are also within the scope of the invention.