89807-39-6

Basic information

• Product Name: 2-Propen-1-one, 3-(dimethylamino)-1-(2-hydroxy-5-methylphenyl)-
• CAS NO: 89807-39-6
• Molecular Formula: C12H15NO2
• Molecular Weight: 205.257
• Mol File: 89807-39-6.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 3-(dimethylamino)-1-(2-hydroxy-5-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 3-(dimethylamino)-1-(2-hydroxy-5-methylphenyl)-(89807-39-6)
• EPA Substance Registry System: 2-Propen-1-one, 3-(dimethylamino)-1-(2-hydroxy-5-methylphenyl)-(89807-39-6)

Safety Data

• Hazardous Substances Data: 89807-39-6(Hazardous Substances Data)

Upstream product

• 1450-72-2 5-methyl-2-hydroxyacetophenone 
• 68-12-2 N,N-dimethyl-formamide 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 42059-81-4 3-formyl-6-methylchromone 
• 124-40-3 dimethyl amine 
• 1188-33-6 N,N-dimethylformamide diethyl diacetal 

Downstream Products

• 1609205-25-5 methyl 4-(cyclohexylamino)-8-methyl-1,3,10-trioxo-2-phenyl-1,2,3,10-tetrahydrochromeno[2,3-f]isoindole-11-carboxylate 
• 1293908-70-9 6-methyl-4-oxo-N-phenyl-4H-chromen-3-carboxamide 
• 1017080-36-2 6-methyl-3-(p-tolyl)-4H-chromen-4-one 
• 130252-75-4 3-(4-methoxyphenyl)-6-methyl-4H-chromen-4-one 
• 1354627-92-1 5-(2-hydroxy-5-methylphenyl)-1-methyl-3-phenyl-1H-imidazo[4,5-b]pyridine-2(3H)-thione 

Relevant articles and documents

Visible Light-Promoted Selenylation/Cyclization of Enaminones toward the Formation of 3-Selanyl-4H-Chromen-4-Ones

A simple and efficient visible-light-promoted selenylation/cyclization of enaminones have been realized for the practical synthesis of 3-selanyl-4H-chromen-4-ones. This reaction is performed in the mild conditions, no transition metal catalyst or photocatalysts and no additional oxidants are required. In addition, the 3-selanyl-4H-chromen-4-ones could be easily converted to selanyl-functionalized pyrimidines by reacting with benzamidine substrates. (Figure presented.).

T3P mediated domino C(sp2)-H sulfenylation/annulation of enaminones and methylsulfinyls for the synthesis of chromone thioether derivatives

A new regioselective method for the synthesis of 3-(methylthio)-4H-chromen-4-one and 3-(phenylthio)-4H-chromen-4-one derivatives has been developed. The reaction between o-hydroxy-phenyl-functionalized enaminones and methylsulfinyl derivatives using T3P gave good yields of chromone thioether derivatives. The reaction proceeds via domino chromone ring construction and C(sp2)-H bond sulfenylation under transition-metal-free conditions.

Application of E1cB Elimination in Asymmetric Organocatalytic Cascade Reactions to Construct Polyheterocyclic Compounds

By introducing a carbon functionality at 2-position of chromane, the formal asymmetric functionalization of the 3-position of 2-substituted chromane has been realized via a highly chemo-, regio-, and stereoselective organocatalytic cascade reaction in a sequential one-pot manner involving an E1cB mechanism governed ring-opening process. Critical to our success was the design of a chiral dipeptide-based bifunctional acid-base organocatalyst, which exhibited high catalytic activity at low catalyst loading (1-0.1 mol %), leading to biologically interesting polyheterocyclic compounds.