900519-23-5Relevant articles and documents
Unified total synthesis of pteriatoxins and their diastereomers
Matsuura, Fumiyoshi,Peters, Rene,Anada, Masahiro,Harried, Scott S.,Hao, Junliang,Kishi, Yoshito
, p. 7463 - 7465 (2007/10/03)
A unified total synthesis is reported to access all of the possible diastereomers of pteriatoxins A-C, with the use of an intramolecular Diels-Alder reaction as the key step to form the carbo-macrocyclic core structure. The C34/C35-diol protecting groups were found to have significant effects on both the exo/endo-selectivity and the exo-facial selectivity of the intramolecular Diels-Alder process. Copyright