91902-58-8 Usage
Description
1-Naphthalenecarboxylicacid, 4-ethyl-, also known as 4-Ethyl-1-naphthoic acid, is an organic compound derived from naphthalene. It possesses a carboxylic acid functional group and an ethyl substituent at the 4-position. 1-Naphthalenecarboxylicacid, 4-ethylis known for its potential applications in various fields, particularly in the synthesis of pharmaceuticals and agrochemicals.
Uses
Used in Pharmaceutical Industry:
1-Naphthalenecarboxylicacid, 4-ethylis used as a key intermediate in the synthesis of antimalarial compounds. Its unique structure allows for the development of drugs that can effectively target and combat malaria-causing parasites, providing a valuable contribution to the treatment and prevention of this widespread disease.
Used in Agrochemical Industry:
1-Naphthalenecarboxylicacid, 4-ethylalso exhibits plant-growth activity, making it a potential candidate for use in the development of agrochemicals and plant growth regulators. By modulating plant growth and development, this compound can contribute to improved crop yields and overall agricultural productivity.
Check Digit Verification of cas no
The CAS Registry Mumber 91902-58-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,9,0 and 2 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 91902-58:
(7*9)+(6*1)+(5*9)+(4*0)+(3*2)+(2*5)+(1*8)=138
138 % 10 = 8
So 91902-58-8 is a valid CAS Registry Number.
InChI:InChI=1/C13H12O2/c1-2-9-7-8-12(13(14)15)11-6-4-3-5-10(9)11/h3-8H,2H2,1H3,(H,14,15)
91902-58-8Relevant articles and documents
Regioselective synthesis of alkylarenes by two-step ipso-substitution of aromatic dicarboxylic acids
Bramborg, Andrea,Linker, Torsten
, p. 5552 - 5563 (2012/11/07)
A strategy for the regioselective alkylation of arenes was developed, starting from commercially available and inexpensive terephthalic acid or naphthalene-1,4-dicarboxylic acid. The method entails a formal ipso-substitution of the carboxylate groups by a sequence of reductive alkylation under Birch conditions and subsequent acid-mediated rearomatization with loss of carbon monoxide and carbon dioxide. More than 20 different arenes with various side-chains were synthesized. With naphthalene-1,4-dicarboxylic acid as starting material, we were able to control the degree of alkylation by choosing the appropriate electrophile in the Birch reduction. Thus, bisalkylated naphthalenes and naphthoic acids became available chemoselectively. All reactions afforded a single regioisomer exclusively in high yields. Overall, aromatic dicarboxylic acids are suitable substrates for a two-step ipso-substitution that allows the selective synthesis of alkylated benzenes and naphthalenes.
CB2-selective cannabinoid analogues
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Page 23, (2010/02/10)
Cannabinoid analogues that exhibit specificity for the CB2 cannabinoid receptor are provided. The analogues are 1-methoxy-, 1-deoxy-11-hydroxy- and 11-hydroxy-1-methoxy-Δ8-tetrahydrocannabinols and 1-alkyl-3(1-naphthoyl)indoles. The compounds are useful for the treatment of pain (especially pain resulting from inflammation) and cancer (especially glioma tumors).
