919079-50-8

Basic information

• Product Name: 3-[6-(2,4-difluoro-phenylamino)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-methoxy-N-(tetrahydro-pyran-4-yl)-benzamide
• CAS NO: 919079-50-8
• Molecular Weight: 609.748
• Mol File: 919079-50-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-[6-(2,4-difluoro-phenylamino)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-methoxy-N-(tetrahydro-pyran-4-yl)-benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[6-(2,4-difluoro-phenylamino)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-methoxy-N-(tetrahydro-pyran-4-yl)-benzamide(919079-50-8)
• EPA Substance Registry System: 3-[6-(2,4-difluoro-phenylamino)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-methoxy-N-(tetrahydro-pyran-4-yl)-benzamide(919079-50-8)

Safety Data

• Hazardous Substances Data: 919079-50-8(Hazardous Substances Data)

Upstream product

• 25016-01-7 5-bromo-2-methoxybenzaldehyde 
• 367-25-9 2,4-difluorophenylamine 
• 2402-78-0 2,6-dichloropyridine 
• 872513-26-3 3-[6-chloro-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-methoxy-benzoic acid 
• 892483-10-2 3-(5-bromo-2-methoxy-phenyl)-6-chloro-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrazolo[3,4-b]pyridine 
• 872513-22-9 3-(5-bromo-2-methoxy-phenyl)-6-chloro-1H-pyrazolo[3,4-b]pyridine 
• 872513-52-5 (5-bromo-2-methoxy-phenyl)-(2,6-dichloro-pyridin-3-yl)-methanol 
• 872513-21-8 (5-bromo-2-methoxy-phenyl)-(2,6-dichloro-pyridin-3-yl)-methanone 
• 38041-19-9 4-aminotetrahydropyran 
• 872513-45-6 3-[6-(2,4-difluoro-phenylamino)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-methoxy-benzoic acid 

Downstream Products

• 872513-47-8 3-[6-(2,4-difluoro-phenylamino)-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-methoxy-N-(tetrahydro-pyran-4-yl)-benzamide 

Relevant articles and documents

Pyrazoloheteroaryls: Novel p38α MAP kinase inhibiting scaffolds with oral activity

A test library with three novel p38α inhibitory scaffolds and a narrow set of substituents was prepared. Appropriate combination of substituent and scaffold generated potent p38α inhibitors, for example, pyrazolo[3,4-b]pyridine 9, pyrazolo[3,4-d]pyrimidin