93782-07-1

Basic information

• Product Name: 2-amino-N-methyl-2-phenylacetamide
• Synonyms: 2-amino-N-methyl-2-phenylacetamide;6-Bromo-1-cyclopentyl-1H,2H,3H-imidazo[4,5-b]pyridin-2-one
• CAS NO: 93782-07-1
• Molecular Formula: C₉H₁₂N₂O
• Molecular Weight: 282.13648
• EINECS: 938-966-9
• Mol File: 93782-07-1.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-amino-N-methyl-2-phenylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-N-methyl-2-phenylacetamide(93782-07-1)
• EPA Substance Registry System: 2-amino-N-methyl-2-phenylacetamide(93782-07-1)

Safety Data

• Hazardous Substances Data: 93782-07-1(Hazardous Substances Data)

Usage

Physical Form

White crystalline powder

Application

Used in pharmaceutical synthesis

Functional Groups

Amino Group (-NH2)
Methyl Group (-CH3)
Phenyl Group (-C6H5)

Potential Uses

Intermediate in organic synthesis
Building block for complex compounds

Safety Precautions

Proper handling and storage required

Hazards

Not specified, but general chemical safety guidelines apply.

Upstream product

• 53059-79-3 2-{[1-(4-Methoxy-phenyl)-meth-(E)-ylidene]-amino}-N-methyl-2-phenyl-acetamide 
• 6097-58-1 ethyl 2-phenyl-2-aminoacetate 
• 74-89-5 methylamine 
• 15028-40-7 DL-2-phenylglycine methyl ester hydrochloride 
• 5840-78-8 4-phenyl-oxazolidine-2,5-dione 
• 2835-06-5 phenylglycin 
• 150884-50-7 benzaldehyde N-boc imine 
• 108-86-1 bromobenzene 
• 875-74-1 (R)-phenylglycine 

Downstream Products

• 78139-29-4 2-methyl-4-phenyl-1,2,5-thiadiazol-3-one 
• 93782-08-2 N-acetyl-D,L-phenylglycine methylamide 
• 1443787-34-5 N¹-(4-chloro-3-fluorophenyl)-N²-(2-(methylamino)-2-oxo-1-phenylethyl)oxalamide 
• 126179-91-7 (R)-N-hexa-4,5-dienyl-N-methyl-1-phenyldimethylene diamine 
• 126179-90-6 (R)-N-methyl-2-(N'-hexa-4,5-dienylamino)-2-phenylacetamide 
• 126179-96-2 N-<(R)-α-N-methyl(aminomethyl)benzyl>-(S)-2-vinylpyrrolidine 
• 126180-08-3 N-<(R)-α-N-methyl(aminomethyl)benzyl>-(R)-2-vinylpyrrolidine 
• 126179-95-1 (R)-N-methyl(phenyl)<(S)-2-vinylpyrrolidin-1-yl>acetamide 
• 126180-07-2 (R)-N-methyl(phenyl)<(R)-2-vinylpyrrolidin-1-yl>acetamide 
• 1236479-69-8 (L)-2-acetylamino-3-(biphenyl-4-yl)-propanoic acid-(R)-2-amino N-methyl-2-phenyl-acetamide salt 
• 1383925-63-0 (R)-(+)-1-methyl-4-phenyl-2-(pyrid-2-yl)imidazoline 
• 61337-91-5 (R)-N¹-methyl-1-phenylethane-1,2-diamine 

Relevant articles and documents

Efficient synthesis of α-amino secondary amides by direct aminocarbonylation of N-Boc-imines using carbamoylsilane as an amide source

A novel and practical procedure for the preparation of α-amino secondary amides by the aminocarbonylation of N-Boc-imines using carbamoylsilanes bearing methoxymethyl group as secondary amides source is presented herein. The protocol tolerates N-Boc-imines bearing different groups, including aryl, double bond conjugated aryl, heteroaryl and aliphatic groups. The reactions provide good to excellent yields of the products under mild and catalysts-free conditions. The electronic property and the steric hindrance of substituent on the N-Boc-imines affect the reaction.

The asymmetric reduction of imidazolinones with trichlorosilane

It is shown how imidazolinones are reduced by trichlorosilane in a highly enantioselective fashion when treated with a novel Lewis base organocatalyst that is based on a 2,2′-bispyrrolidine core. Under mild reaction conditions and with low catalyst loading the hydrosilylation reaction provides a broad range of chiral imidazolidinones with various structural motifs including sterically demanding substituents, alkyls and aryls.

INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF MIRTAZAPINE AND THE PRODUCTION METHODS THEREOF

Intermediate compounds for the preparation of mirtazapine and obtention methods thereof. A method is described for obtaining (±)-3-phenyl-1-methylpiperazine, an important intermediate for obtaining mirtazapine, which is based on imposing a cyclation reaction, in the presence of a reducing agent, on new compounds of general formula (I) in which Z is a leaving group capable of undergoing a nucleophylic displacement. A method is also described for obtaining the new compounds of formula (I).