97760-95-7

Basic information

• Product Name: Acetamide, N-(2-fluoro-4-formylphenyl)-
• CAS NO: 97760-95-7
• Molecular Formula: C9H8FNO2
• Molecular Weight: 181.166
• Mol File: 97760-95-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Acetamide, N-(2-fluoro-4-formylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-(2-fluoro-4-formylphenyl)-(97760-95-7)
• EPA Substance Registry System: Acetamide, N-(2-fluoro-4-formylphenyl)-(97760-95-7)

Safety Data

• Hazardous Substances Data: 97760-95-7(Hazardous Substances Data)

Upstream product

• 97760-94-6 N-(2-fluoro-4-iodo-phenyl)-acetamide 
• 29632-74-4 2-fluro-4-iodoaniline 
• 348-54-9 2-Fluoroaniline 
• 93129-68-1 4-acetylamino-3-fluoro-benzonitrile 
• 122-85-0 para-acetamidobenzaldehyde 

Downstream Products

• 85117-88-0 4'-acetylamino-3'-fluoro-acetophenone 
• 54240-29-8 1-(4-Amino-3-bromo-5-fluoro-phenyl)-2-(2-benzo[1,3]dioxol-5-yl-1-methyl-ethylamino)-ethanone 
• 54238-93-6 1-(4-Amino-3-chloro-5-fluoro-phenyl)-2-(2-benzo[1,3]dioxol-5-yl-1-methyl-ethylamino)-ethanone 
• 56340-31-9 4'-amino-3'-cyano-2-cyclopentylamino-5'-fluoroacetophenone 
• 56340-10-4 1-(4-Amino-3-bromo-5-fluoro-phenyl)-2-cycloheptylamino-ethanone 
• 56340-27-3 4'-amino-3'-cyano-2-cyclobutylamino-5'-fluoroacetophenone 
• 56340-25-1 4'-amino-3'-cyano-5'-fluoro-2-isopropylaminoacetophenone 
• 56340-23-9 4'-amino-3'-cyano-2-cyclopropylamino-5'-fluoroacetophenone 
• 771433-92-2 4'-acetylamino-3'-fluoro-2-isopropylamino-acetophenone 
• 56340-33-1 4'-amino-3'-cyano-5'-fluoro-2-tert-pentylaminoacetophenone 
• 685496-26-8 1-(4-Amino-3-chloro-5-fluoro-phenyl)-2-isopropylamino-ethanone 
• 690978-36-0 4'-acetylamino-2-bromo-3'-fluoro-acetophenone 

Relevant articles and documents

PHENYLALKYL AND PYRIDYLALKYL PIPERAZINE DERIVATIVES

This invention relates to compounds of the formula (1) wherein R1, R3, R4, X1, and X2 are defined as in the specification, pharmaceutical compositions containing them and their use in the treatment of central nervous system and other disorders.

Synthesis of further amino-halogen-substituted phenyl-aminoethanols

Starting from clenbuterol as a lead structure, new 4-amino-phenyl-aminoethanol analogues have been synthesized by different approaches. In these compounds one or both of the chlorine atoms of clenbuterol are replaced by other residues. This has led to compounds with high intrinsic β2-mimetic and/or β1-blocking activities. 1-(4-Amino-3-chloro-5-trifluoromethyl-phenyl)-2-tert.-butylamino-ethanol hydrochloride (mabuterol) has been selected for clinical development. A detailed description is also given of the syntheses of new intermediate acetophenone derivatives as well as of the resolution of mabuterol into its enantiomers.