99179-39-2

Basic information

• Product Name: Acetaldehyde, (2-methylphenoxy)-
• CAS NO: 99179-39-2
• Molecular Formula: C9H10O2
• Molecular Weight: 150.177
• Mol File: 99179-39-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Acetaldehyde, (2-methylphenoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetaldehyde, (2-methylphenoxy)-(99179-39-2)
• EPA Substance Registry System: Acetaldehyde, (2-methylphenoxy)-(99179-39-2)

Safety Data

• Hazardous Substances Data: 99179-39-2(Hazardous Substances Data)

Upstream product

• 936-72-1 allyl o-tolyl ether 
• 95-46-5 2-methylphenyl bromide 
• 6161-86-0 2-methylphenoxyethanol 
• 95-48-7 ortho-cresol 
• 2210-79-9 o-Cresyl glycidyl ether 
• 59-47-2 mephenesin 

Downstream Products

• 103195-89-7 2-(o-tolyloxymethyl)thiazolidine 
• 17059-52-8 7-methylbenzofuran 
• 119904-32-4 2-methylphenoxyacetaldehyde cyanohydrin acetate 
• 104730-53-2 (S)-2-methylphenoxyacetaldehyde cyanohydrin acetate 
• 95333-18-9 2-methylphenoxyacetaldehyde dimethyl acetal 
• 74953-42-7 2-methylphenoxyacetaldehyde cyanohydrin 
• 134671-21-9 2C₁₀H₁₄N₄O₂*H₂O₄S 
• 94757-30-9 2,5-Dihydroxy-1,6-(o-tolyloxy)-hex-3-in 
• 91142-51-7 2-Hydroxy-1-(o-tolyloxy)-but-3-in 
• 64899-61-2 4-o-tolyloxy-trans-crotonic acid 

Relevant articles and documents

Copper(ii)-catalyzed C-O coupling of aryl bromides with aliphatic diols: Synthesis of ethers, phenols, and benzo-fused cyclic ethers

A highly efficient copper-catalyzed C-O cross-coupling reaction between aryl bromides and aliphatic diols has been developed employing a cheaper, more efficient, and easily removable copper(ii) catalyst. A broad range of aryl bromides were coupled with aliphatic diols of different lengths using 5 mol% CuCl2 and 3 equivalents of K2CO3 in the absence of any other ligands or solvents to afford the corresponding hydroxyalkyl aryl ethers in good to excellent yields. In this newly developed protocol, aliphatic diols have multilateral functions as coupling reactants, ligands, and solvents. The resulting hydroxyalkyl aryl ethers were further readily converted into the corresponding phenols, presenting a valuable alternative way to phenols from aryl bromides. Furthermore, it was demonstrated that they are useful intermediates for more advanced molecules such as benzofurans and benzo-fused cyclic ethers. This journal is

Ozonolysis of Olefins VIII [1]. Synthesis of Phenoxyacetaldehydes by Ozonolysis of Allylphenylethers

A new route for the preparation of a series of phenoxyacetaldehydes (2a-j) which are useful intermediates or products, is described. It starts from the easily available allylphenylethers 1a-j which are ozonized at -40°C and further treated with dimethylsulfide to give solutions of the corresponding phenoxyacetaldehydes 2a-j; these are purified by column chromatography. Reaction of 2a-j with 1-methyl-1-phenylhydrazine leads to the corresponding hydrazones 3a-c, 3e-g, 3i, and 3j. The aldehydes can also be transformed into the stable dimethylcetals 4a, 4e, 4h, and 4i by reaction with trimethyl orthoformate.

Formation of Optically Active Aryloxyacetaldehyde Cyanohydrin Acetates with the Aid of a Microorganism

Microorganisms that hydrolyze the one enantiomer of dl-phenoxyacetaldehyde cyanohydrin acetate were screened, and Bacillus coagulans isolated from soil was found to be the best.This bacterium was applied to the asymmetric hydrolysis of other aryloxyacetaldehyde derivatives to give satisfactory results.The effect of adding dimethyl sulfoxide to the medium is also described.