1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE supplier

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Name
1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE
EINECS
CAS No. 4764-17-4
Article Data28
CAS DataBase
Density 1.163g/cm³
Solubility
Melting Point 178-179 °C
Formula C₁₀H₁₃NO₂
Boiling Point 281.7°C at 760 mmHg
Molecular Weight 179.219
Flash Point 134.9°C
Transport Information
Appearance
Safety Poison by ingestion, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NO_x. See also AMINES and BENZEDRINE.
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms Tenamphetamine;8-hydroxymethyl-1,2,3,5,6,7,8,9-octahydroindolizine;3,4-methylenedioxyamphetamine;rac-3,4-methylenedioxyamphetamine;3,4-methylenedioxyphenylisopropylamine;
PSA 44.48000
LogP 2.00530

1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE Chemical Properties

Molecular formula: C₁₀H₁₃NO₂
Molar mass: 179.22
Structure of 1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE(4764-17-4):

Synonyms of 1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE(4764-17-4): 1-(1,3-Benzodioxol-5-yl)-2-propanamine;alpha-methyl-1,3-benzodioxole-5-ethanamine;1,3-Benzodioxole-5-ethanamine, alpha-methyl-;alpha-methyl-3,4-(methylenedioxy)-phenethylamin;alpha-methyl-3-benzodioxole-5-ethanamine;alpha-Methyl-3,4-(methylenedioxy)phenethylamine;mda(pharmaceutical);Methylenedioxyamphetamine.

1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE History

1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE(4764-17-4) was first synthesized by G. Mannish and W. Jacobson in 1910.
Researchers have investigated many possible uses in the past,but there are no currently accepted medical uses for 1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE(4764-17-4).
1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE(4764-17-4) was first ingested in July of 1930 by Gordon Alles who then licensed the drug to Smith Kline and French.
1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE(4764-17-4) was first used in animal tests in 1939, and human trials began in 1941 in the exploration of possible therapies for Parkinson's disease. More than 500 human subjects were given 1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE(4764-17-4) in an investigation of its potential use as an antidepressant and/or anorectic by Smith, Kline & French from 1949 to 1957. The United States Army also experimented with the drug. MDA was patented as a cough suppressant by H. D. Brown in 1958 and as an anorectic in 1961.

1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE Uses

Although it's inexpensive ,1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE(4764-17-4) is readily available as a research chemical from several scientific supply houses .

1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE Production

Synthesis of 1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE(4764-17-4) is to turn safrole into isosafrole via isomerization.
The most common route of 1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE(4764-17-4) is by starting from piperonal, and condensing it with nitroethane, then with a suitable reducing agent The resulting nitro-isosafrole can be reduced to 1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE(4764-17-4) .

1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE Toxicity Data With Reference

1.	orl-mus LD50:13,300 µg/kg	CTOXAO Clinical Toxicology. 6 (1973),193.
2.	ipr-mus LD50:82,300 µg/kg	CTOXAO Clinical Toxicology. 6 (1973),193.
3.	ivn-mus LD50:31,100 µg/kg	TRBMAV Texas Reports on Biology and Medicine. 33 (1975),610.

1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE Safety Profile

Poison by ingestion, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NO_x. See also AMINES and BENZEDRINE.

1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE Specification

In 1970, in the United States, placing 1-(1,3-BENZODIOXOL-5-YL) PROPAN-2-AMINE(4764-17-4) was placed into Schedule I. but 1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE(4764-17-4) is similarly controlled in other nations.
3,4-Methylenedioxyamphetamine (MDA) is a psychedelic, stimulant, and empathogen-entactogen of the phenethylamine and amphetamine chemical classes.

Product Name

1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE