-
Name
Lefetamine hydrochloride
- EINECS
- CAS No. 14148-99-3
- Density
- Solubility
- Melting Point 218-219°
- Formula C16H19 N . Cl H
- Boiling Point
- Molecular Weight 261.82
- Flash Point
- Transport Information
- Appearance
- Safety Poison by ingestion, intravenous, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of HCl and NOx.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms Benzeneethanamine,N,N-dimethyl-a-phenyl-,hydrochloride, (R)-; Ethylamine, N,N-dimethyl-1,2-diphenyl-, hydrochloride,(R)(-)- (8CI); Lefetamine hydrochloride; SPA; SPA (analgesic)
- PSA 3.24000
- LogP 4.33400
1,2-Diphenyl-1-(dimethylamino)ethane Chemical Properties
IUPAC Name: 1,2-Diphenylethyl(dimethyl)azanium chloride
Molecular Formula: C16H19N•ClH
Molecular Weight: 261.82
Freely Rotating Bonds: 4
Polar Surface Area: 3.24 Å2
Index of Refraction: 1.568
Molar Refractivity: 73.27 cm3
Molar Volume: 223.9 cm3
Polarizability: 29.05 ×10-24 cm3
Surface Tension: 39 dyne/cm
Density: 1.006 g/cm3
Flash Point: 121 °C
Enthalpy of Vaporization: 53.52 kJ/mol
Boiling Point: 295.5 °C at 760 mmHg
Vapour Pressure: 0.00152 mmHg at 25°C
The Cas Register Number of 1,2-Diphenyl-1-(dimethylamino)ethane is 14148-99-3 .The chemical synonyms of 1,2-Diphenyl-1-(dimethylamino)ethane (CAS NO.14148-99-3) are Benzeneethanamine, N,N-dimethyl-alpha-phenyl-, (R)- ; Lefetamine .The molecular structure of 1,2-Diphenyl-1-(dimethylamino)ethane (CAS NO.14148-99-3) is
.
1,2-Diphenyl-1-(dimethylamino)ethane Uses
1,2-Diphenyl-1-(dimethylamino)ethane (CAS NO.14148-99-3) is used as organic intermediate .
1,2-Diphenyl-1-(dimethylamino)ethane Toxicity Data With Reference
| 1. | orl-rat LD50:300 mg/kg | DRFUD4 Drugs of the Future. 2 (1977),39. | ||
| 2. | scu-rat LD50:148 mg/kg | AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 221 (1976),105. | ||
| 3. | orl-mus LD50:176 mg/kg | DRFUD4 Drugs of the Future. 2 (1977),39. | ||
| 4. | scu-mus LD50:104 mg/kg | DRFUD4 Drugs of the Future. 2 (1977),39. | ||
| 5. | ivn-mus LD50:32,600 µg/kg | DRFUD4 Drugs of the Future. 2 (1977),39. |
1,2-Diphenyl-1-(dimethylamino)ethane Safety Profile
Poison by ingestion, intravenous, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of HCl and NOx.
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