2,2,3,3,3-PENTAFLUOROPROPYLAMINE HYDROCHLORIDE

The 1-Propanamine,2,2,3,3,3-pentafluoro-, hydrochloride (1:1), with the CAS registry number 374-14-1, is also known as 2,2,3,3,3-Pentafluoro-1-propanaminium chloride. This chemical's molecular formula is C₃H₅ClF₅N and molecular weight is 185.52. What's more, its IUPAC name is called 2,2,3,3,3-Pentafluoropropan-1-amine hydrochloride.

Physical properties about 1-Propanamine,2,2,3,3,3-pentafluoro-, hydrochloride (1:1) are: (1)ACD/LogP: 1.507; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.97; (4)ACD/LogD (pH 7.4): 1.49; (5)ACD/BCF (pH 5.5): 2.39; (6)ACD/BCF (pH 7.4): 7.98; (7)ACD/KOC (pH 5.5): 45.62; (8)ACD/KOC (pH 7.4): 152.60; (9)#H bond acceptors: 1; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 0 Å²; (13)Flash Point: 15.1 °C; (14)Enthalpy of Vaporization: 28.72 kJ/mol; (15)Boiling Point: 43 °C at 760 mmHg ; (16)Vapour Pressure: 383 mmHg at 25 °C.

Uses of 1-Propanamine,2,2,3,3,3-pentafluoro-, hydrochloride (1:1): it is used to produce other chemicals. For example, it can react with iodoacetic acid to get 2-iodo-N-(2,2,3,3,3-pentafluoro-propyl)-acetamide. The reaction occurs with reagents N-methylmorpholine, iso-butyl chloroformate and solvent tetrahydrofuran at temperature of 20 °C. The reaction time is 20 hours. The yield is 53 %.

When you are dealing with this chemical, you should be very careful. This chemical is inflammation to the skin, eyes and respiratory system or other mucous membranes. Therefore, you should wear suitable protective clothing, gloves and eye/face protection. In case of contacting with eyes, you should rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1) SMILES: [Cl-].FC(F)(C[NH3+])C(F)(F)F
(2) InChI: InChI=1S/C3H4F5N.ClH/c4-2(5,1-9)3(6,7)8;/h1,9H2;1H
(3) InChIKey: InChI=1S/C3H4F5N.ClH/c4-2(5,1-9)3(6,7)8;/h1,9H2;1H