2,3,5,6-Tetrafluoro-1,4-benzenedimethanol

The 1,4-Benzenedimethanol,2,3,5,6-tetrafluoro-, with the CAS registry number 92339-07-6, is also known as Tetrafluoro-4-(hydroxymethyl)phenyl]methanol. It belongs to the product category of Aromatic Halides (substituted). This chemical's molecular formula is C₈H₆F₄O₂ and molecular weight is 210.13. What's more, its systematic name is (2,3,5,6-Tetrafluoro-1,4-phenylene)dimethanol.

Physical properties of 1,4-Benzenedimethanol,2,3,5,6-tetrafluoro- are: (1)ACD/LogP: -0.129; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -0.13; (4)ACD/LogD (pH 7.4): -0.13; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 20.27; (8)ACD/KOC (pH 7.4): 20.27; (9)#H bond acceptors: 2; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 4; (12)Polar Surface Area: 40.46 Å²; (13)Index of Refraction: 1.496; (14)Molar Refractivity: 39.131 cm³; (15)Molar Volume: 133.905 cm³; (16)Polarizability: 15.513×10^-24cm³; (17)Surface Tension: 42.98 dyne/cm; (18)Density: 1.569 g/cm³; (19)Flash Point: 108.613 °C; (20)Enthalpy of Vaporization: 52.139 kJ/mol; (21)Boiling Point: 255.979 °C at 760 mmHg; (22)Vapour Pressure: 0.008 mmHg at 25°C.

Preparation: this chemical can be prepared by 2,3,5,6-tetrafluoro-benzene-1,4-dicarbaldehyde at the temperature of 0 °C. This reaction will need reagent (CH₃)₂S·BH₃ and solvent tetrahydrofuran with the reaction time of 15 min. The yield is about 83%.

Uses of 1,4-Benzenedimethanol,2,3,5,6-tetrafluoro-: it can be used to produce 1,4-bis-chloromethyl-2,3,5,6-tetrafluoro-benzene by heating. It will need reagent SOCl₂ with the reaction time of 5 hours. The yield is about 97%.

You can still convert the following datas into molecular structure:
(1)SMILES: Fc1c(c(F)c(F)c(c1F)CO)CO
(2)Std. InChI: InChI=1S/C8H6F4O2/c9-5-3(1-13)6(10)8(12)4(2-14)7(5)11/h13-14H,1-2H2
(3)Std. InChIKey: SDHKGYDQOGCLQM-UHFFFAOYSA-N