2,3-Difluoroanisole

The 2,3-Difluoroanisole, with the CAS registry number 134364-69-5, is also known as 2,3-Difluorophenyl methyl ether. It belongs to the product categories of Blocks; Fluoro Compounds; Aromatic Halides (substituted); Phenyls & Phenyl-Het; Fluorobenzene. This chemical's molecular formula is C₇H₆F₂O and molecular weight is 144.12. What's more, its systematic name is 1,2-difluoro-3-methoxybenzene. It should be sealed and stored in a cool and dry place. Moreover, it should be ensured that the workshop is well ventilated or equipped with exhaust devices.

Physical properties of 2,3-Difluoroanisole are: (1)ACD/LogP: 2.15; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.15; (4)ACD/LogD (pH 7.4): 2.15; (5)ACD/BCF (pH 5.5): 25.22; (6)ACD/BCF (pH 7.4): 25.22; (7)ACD/KOC (pH 5.5): 350.76; (8)ACD/KOC (pH 7.4): 350.76; (9)#H bond acceptors: 1; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 9.23 Å²; (13)Index of Refraction: 1.452; (14)Molar Refractivity: 32.91 cm³; (15)Molar Volume: 121.8 cm³; (16)Polarizability: 13.05×10^-24cm³; (17)Surface Tension: 27.1 dyne/cm; (18)Density: 1.182 g/cm³; (19)Flash Point: 47.1 °C; (20)Enthalpy of Vaporization: 36.58 kJ/mol; (21)Boiling Point: 144.5 °C at 760 mmHg; (22)Vapour Pressure: 6.4 mmHg at 25°C.

Uses of 2,3-Difluoroanisole: it can be used to produce 2,3-difluoro-4-methoxy-benzaldehyde and 3,4-difluoro-2-methoxy-benzaldehyde at the temperature of 20 °C. It will need reagent TiCl₄ and solvent CH₂Cl₂ with the reaction time of 30 min. The yield is about 71%.

When you are using this chemical, please be cautious about it as the following:
This chemical is flammable, so you should keep it away from sources of ignition - No smoking. It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. When using it, you need wear suitable protective clothing.

You can still convert the following datas into molecular structure:
(1)SMILES: Fc1c(F)cccc1OC
(2)Std. InChI: InChI=1S/C7H6F2O/c1-10-6-4-2-3-5(8)7(6)9/h2-4H,1H3
(3)Std. InChIKey: RDOGTTNFVLSBKG-UHFFFAOYSA-N