-
Name
2,4-Difluoroaniline
- EINECS 206-687-5
- CAS No. 367-25-9
- Article Data32
- CAS DataBase
- Density 1.289 g/cm3
- Solubility 1-5 g/100 mL at 20.55 °C in water
- Melting Point -7.5 °C(lit.)
- Formula C6H5F2N
- Boiling Point 168.4 °C at 760 mmHg
- Molecular Weight 129.109
- Flash Point 62.8 °C
- Transport Information UN 2941 6.1/PG 3
- Appearance dark red liquid
- Safety 28-36/37/39-26
- Risk Codes 20/21/22-36/37/38
-
Molecular Structure
-
Hazard Symbols
Xn， 
Xi， 
T
- Synonyms Benzenamine, 2,4-difluoro-;2,5- Difluoroaniline;4-12-00-01112 (Beilstein Handbook Reference);2,4-Difluorobenzenamine;Aniline, 2,4-difluoro-;2,4-Difluorobenzeneamine;2,4-Difluoro-benzenamine;1-Amino-2,4-difluorobenzene;
- PSA 26.02000
- LogP 2.12820
2,4-Difluoroaniline Chemical Properties
Molecular Structure:
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Molecular Formula: C6H5F2N
Molecular Weight: 129.1074
IUPAC Name: 2,4-Difluoroaniline
Synonyms of 2,4-Difluoroaniline (CAS NO.367-25-9): 2,4-Difluorobenzenamine ; 4-12-00-01112 (Beilstein Handbook Reference) ; AI3-52650 ; BRN 2802556 ; CCRIS 4621 ; EINECS 206-687-5 ; NSC 10297 ; Aniline, 2,4-difluoro- ; Benzenamine, 2,4-difluoro-
CAS NO: 367-25-9
Classification Code: Mutation data
Melting point: −7.5 °C
Index of Refraction: 1.52
Molar Refractivity: 30.47 cm3
Molar Volume: 100.1 cm3
Surface Tension: 37.2 dyne/cm
Density: 1.289 g/cm3
Flash Point: 62.8 °C
Enthalpy of Vaporization: 40.49 kJ/mol
Boiling Point: 168.4 °C at 760 mmHg
Vapour Pressure: 1.62 mmHg at 25°C
2,4-Difluoroaniline Uses
2,4-Difluoroaniline (CAS NO.367-25-9) can be used as intermediates of Pharmaceutical and pesticide .
2,4-Difluoroaniline Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| rat | LC50 | inhalation | 6210mg/m3/4H (6210mg/m3) | National Technical Information Service. Vol. OTS0559577, | |
| rat | LD50 | oral | 820mg/kg (820mg/kg) | National Technical Information Service. Vol. OTS0559577, | |
| rat | LD50 | skin | 672mg/kg (672mg/kg) | National Technical Information Service. Vol. OTS0559577, |
2,4-Difluoroaniline Consensus Reports
Reported in EPA TSCA Inventory.
2,4-Difluoroaniline Safety Profile
Hazard Codes of 2,4-Difluoroaniline (CAS NO.367-25-9): 
Xn,
T,
Xi
Risk Statements: 20/21/22-36/37/38
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 28-36/37/39-26
S28: After contact with skin, wash immediately with plenty of soap-suds.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
RIDADR: UN 2941 6.1/PG 3
WGK Germany: 1
RTECS: BX3680000
F: 8-9-23
Hazard Note: Toxic
TSCA: T
HazardClass: 6.1
PackingGroup: III
HS Code 29214210
Mutation data reported. When heated to decomposition it emits toxic vapors of NOx and F−.
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