2,5-Dibromoterephthalic acid supplier

Name
2,5-Dibromoterephthalic acid
EINECS 237-300-8
CAS No. 13731-82-3
Article Data33
CAS DataBase
Density 2.205g/cm3
Solubility
Melting Point 315-318 ºC
Formula C8H4 Br2 O4
Boiling Point 445ºC at 760 mmHg
Molecular Weight 323.925
Flash Point 222.9°C
Transport Information
Appearance
Safety S26;S37/39
Risk Codes R36/37/38
Molecular Structure
Hazard Symbols
Synonyms Terephthalicacid, 2,5-dibromo- (6CI,7CI,8CI); 1,4-Dibromo-2,5-benzenedicarboxylic acid;2,5-Dibromo-4-carboxybenzoic acid; 2,5-Dibromoterephthalic acid; NSC 115430
PSA 74.60000
LogP 2.60800

Synthetic route

: 1074-24-4
2,5-dibromo-p-xylene

: 13731-82-3
2,5-dibromoterephtalic acid

Conditions

Conditions	Yield
With pyridine; potassium permanganate In water	96%
With pyridine; potassium permanganate In water for 24h; Reflux;	91%
With chromium(VI) oxide; sulfuric acid In acetic acid at 20℃; for 24h;	90%

: 20871-01-6
2,5-dibromo-4-methylbenzoic acid

: 13731-82-3
2,5-dibromoterephtalic acid

Conditions

Conditions	Yield
With potassium permanganate; sodium hydrogencarbonate for 144h; Heating;	94%
With potassium permanganate In water for 144h; Reflux;	86%
With potassium permanganate; water for 144h; Reflux;	86%
With alkaline permanganate
With potassium permanganate; potassium carbonate

: 18870-11-6
2,5-dibromobenzene-1,4-dinitrile

: 13731-82-3
2,5-dibromoterephtalic acid

Conditions

Conditions	Yield
With sodium hydroxide

2.5-dibromo-1.4-bis-tribromomethyl-benzene: 2.5-dibromo-1.4-bis-tribromomethyl-benzene

: 13731-82-3
2,5-dibromoterephtalic acid

Conditions

Conditions	Yield
With sulfuric acid at 120 - 130℃;

2.5-dibromo-cymene: 2.5-dibromo-cymene

: 13731-82-3
2,5-dibromoterephtalic acid

Conditions

Conditions	Yield
With nitric acid at 180℃; im geschlossenen Rohr;

: 67-56-1
methanol

: 13731-82-3
2,5-dibromoterephtalic acid

: 18014-00-1
dimethyl 2,5-dibromoterephthalate

Conditions

Conditions	Yield
With thionyl chloride for 5h; Reflux;	100%
With sulfuric acid Heating;	95%
With sulfuric acid Heating; Reflux;	95%

: 13731-82-3
2,5-dibromoterephtalic acid

: 13815-90-2
3,6-dibromo-2,5-phenylenedi(carboxylic acid chloride)

Conditions

Conditions	Yield
With oxalyl dichloride; N,N-dimethyl-formamide In benzene at 80℃;	100%
With oxalyl dichloride	100%
With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane for 3h; Inert atmosphere; Reflux;	100%

: 743460-48-2
biphenyl-2-ylcarbamic acid 1-[2-(methylamino)ethyl]piperidin-4-yl ester

: 13731-82-3
2,5-dibromoterephtalic acid

: 864751-39-3
N-{2-[4-(Biphenyl-2-ylcarbamoyloxy)piperidin-1-yl]ethyl}-2,5-dibromo-N-methylterephthalamic Acid

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; HATU In DMF (N,N-dimethyl-formamide) at 20℃; for 3h;	100%

: 64-17-5
ethanol

: 13731-82-3
2,5-dibromoterephtalic acid

: 18013-97-3
2,5-dibromo-terephthalic acid diethyl ester

Conditions

Conditions	Yield
Stage #1: 2,5-dibromoterephtalic acid With thionyl chloride for 4h; Reflux; Stage #2: ethanol In tetrahydrofuran for 10h;	99%
sulfuric acid Reflux;	96%
With sulfuric acid for 48h; Reflux;	96%

: 13731-82-3
2,5-dibromoterephtalic acid

: 1401211-90-2
N-(2-hexyldecyl)thiophene-3-amine

: 2,5-dibromo-N1,N4-bis(2-hexyldecyl)-N1,N4-di(thiophen-3-yl)terephthalamide

Conditions

Conditions	Yield
Stage #1: 2,5-dibromoterephtalic acid With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 20℃; for 20h; Schlenk technique; Inert atmosphere; Stage #2: N-(2-hexyldecyl)thiophene-3-amine With triethylamine In dichloromethane at 0 - 20℃; for 20h;	99%

: 13731-82-3
2,5-dibromoterephtalic acid

: 610-92-4
2,5-dihydroxy-1,4-benzenedicarboxylic acid

Conditions

Conditions	Yield
Stage #1: 2,5-dibromoterephtalic acid With water; sodium carbonate; trans-N,N'-dimethylcyclohexane-1,2-diamine; copper(I) bromide In acetonitrile at 90℃; for 18h; Stage #2: With hydrogenchloride In water; acetonitrile at 25℃; Product distribution / selectivity;	98%
Stage #1: 2,5-dibromoterephtalic acid With water; sodium carbonate for 1h; Heating / reflux; Stage #2: With water; trans-N,N'-dimethylcyclohexane-1,2-diamine; copper(I) bromide at 90℃; for 2h; Stage #3: With hydrogenchloride In water at 25℃; Product distribution / selectivity;	97%
Stage #1: 2,5-dibromoterephtalic acid With water; sodium carbonate for 1h; Heating / reflux; Stage #2: 2,2,6,6-tetramethylheptane-3,5-dione; copper(I) bromide In water at 80℃; for 30h; Stage #3: With hydrogenchloride In water at 25℃;	92%

: 13731-82-3
2,5-dibromoterephtalic acid

: 124-41-4
sodium methylate

: C10H8O6(2-)*2Na(1+)

Conditions

Conditions	Yield
(±)-N,N-dimethyl-trans-1,2-diaminocyclohexane; copper(ll) bromide In methanol for 8h; Heating / reflux;	95%
2,2,6,6-tetramethylheptane-3,5-dione; copper(ll) bromide In methanol for 8h; Heating / reflux;
1,2-bis[(2,4,6-trimethylphenyl)imino]-1,2-dimethylethane; copper(ll) bromide In methanol for 8h; Heating / reflux;

: 13731-82-3
2,5-dibromoterephtalic acid

: 50880-39-2
2,5-dibromobenzene-1,4-carboxamide

Conditions

Conditions	Yield
Stage #1: 2,5-dibromoterephtalic acid With thionyl chloride; N,N-dimethyl-formamide for 3h; Inert atmosphere; Reflux; Stage #2: With ammonium hydroxide In 1,4-dioxane for 1h;	94%
Multi-step reaction with 2 steps 1: PCl5 2: diethyl ether; ammonia View Scheme
Multi-step reaction with 2 steps 1: thionyl chloride; N,N-dimethyl-formamide / 3 h / Reflux 2: ammonium hydroxide / 1,4-dioxane / 20 °C View Scheme

: 13731-82-3
2,5-dibromoterephtalic acid

A: 636-94-2
2-hydroxyterephthalic acid

B: 610-92-4
2,5-dihydroxy-1,4-benzenedicarboxylic acid

Conditions

Conditions	Yield
Stage #1: 2,5-dibromoterephtalic acid With sodium carbonate In water for 1h; Heating / reflux; Stage #2: With water; 2,2,6,6-tetramethylheptane-3,5-dione; copper(I) bromide at 80℃; for 30h; Stage #3: With hydrogenchloride In water at 25℃;	A n/a B 92%

: 13731-82-3
2,5-dibromoterephtalic acid

: 71-36-3
butan-1-ol

: 58613-36-8
dibutyl 2,5-dibromoterephthalate

Conditions

Conditions	Yield
With sulfuric acid at 120℃; for 12h;	89%
With sulfuric acid for 15h;	81%

: cobalt(II) nitrate hexahydrate

: 83524-76-9
4,4'-methylenebis(3,5-dimethylpyrazole)

: 13731-82-3
2,5-dibromoterephtalic acid

: {[Co(methylenebis(3,5-dimethylpyrazole))(Br-BDC)](H2O)0.5}

Conditions

Conditions	Yield
In water at 120℃; for 24h; Autoclave;	82%

...Expand

: cadmium(II) nitrate tetrhydrate

: 83524-76-9
4,4'-methylenebis(3,5-dimethylpyrazole)

: 13731-82-3
2,5-dibromoterephtalic acid

: [Cd(methylenebis(3,5-dimethylpyrazole))(Br-BDC)0.5(Br-HBDC)]

Conditions

Conditions	Yield
In water at 120℃; for 48h; Autoclave;	79%

...Expand

: 64-18-6
formic acid

: cobalt(II) nitrate hexahydrate

: 13731-82-3
2,5-dibromoterephtalic acid

: 68-12-2, 33513-42-7
N,N-dimethyl-formamide

: [Co2(2,5-dibromoterephthalate)(HCOO)2(dimethylformamide)2]

Conditions

Conditions	Yield
at 150℃; for 24h; Autoclave; High pressure;	78.2%

...Expand

: 76-37-9
2,2,3,3-tetrafluoropropanol

: 13731-82-3
2,5-dibromoterephtalic acid

: 1268628-20-1
2,5-bis(2,2,3,3-tetrafluoropropoxy)terephthalic acid

Conditions

Conditions	Yield
Stage #1: 2,2,3,3-tetrafluoropropanol With sodium hydride In tetrahydrofuran Stage #2: 2,5-dibromoterephtalic acid; cis-N,N'-dimethyl-1,2-diaminocyclohexane; copper(ll) bromide In tetrahydrofuran; 2,2,3,3-tetrafluoropropanol at 60℃; for 48h; Stage #3: With hydrogenchloride In tetrahydrofuran; water	72%
Stage #1: 2,2,3,3-tetrafluoropropanol With sodium hydride In tetrahydrofuran Stage #2: 2,5-dibromoterephtalic acid; cis-N,N'-dimethyl-1,2-diaminocyclohexane; copper(ll) bromide In tetrahydrofuran; 2,2,3,3-tetrafluoropropanol at 60℃; for 48h; Stage #3: With hydrogenchloride In tetrahydrofuran; water	72%
Stage #1: 2,2,3,3-tetrafluoropropanol With sodium hydride In tetrahydrofuran Stage #2: 2,5-dibromoterephtalic acid; N-Methylanthranilic acid; copper(ll) bromide In tetrahydrofuran; 2,2,3,3-tetrafluoropropanol at 60℃; for 48h; Stage #3: With hydrogenchloride In tetrahydrofuran; water
Stage #1: 2,2,3,3-tetrafluoropropanol With sodium hydride In tetrahydrofuran Stage #2: 2,5-dibromoterephtalic acid; 2,3-bis[N,N-(2-trifluoromethylphenyl)imino]butane; copper(ll) bromide In tetrahydrofuran; 2,2,3,3-tetrafluoropropanol at 60℃; for 48h; Stage #3: With hydrogenchloride In tetrahydrofuran; water
Stage #1: 2,2,3,3-tetrafluoropropanol With sodium hydride In tetrahydrofuran Stage #2: 2,5-dibromoterephtalic acid; acetylacetone; copper(ll) bromide In tetrahydrofuran; 2,2,3,3-tetrafluoropropanol at 60℃; for 48h; Stage #3: With hydrogenchloride In tetrahydrofuran; water

: 553-26-4
4,4'-bipyridine

: 13731-82-3
2,5-dibromoterephtalic acid

: 114460-21-8
calcium acetate hydrate

: (4,4′-bpy)0.5[Ca(dbt)(H2O)2]n

Conditions

Conditions	Yield
With potassium hydroxide In ethanol; water at 120℃; for 72h; Sealed tube; High pressure;	72%

...Expand

2,5-dibromoterephtalic acid: 2,5-dibromoterephtalic acid

: 114460-21-8
calcium acetate hydrate

Conditions

Conditions	Yield
With potassium hydroxide In ethanol; water at 120℃; for 72h; Sealed tube; High pressure;	72%

...Expand

2,5-dibromoterephtalic acid: 2,5-dibromoterephtalic acid

: 197370-00-6
(2,5-dibromo-1,4-phenylene)bis((4-butylphenyl)methanone)

Conditions

Conditions	Yield
Stage #1: 2,5-dibromoterephtalic acid With thionyl chloride for 10h; Reflux; Stage #2: 1-butylbenzene With aluminium trichloride In dichloromethane at 25℃; for 2h;	72%

: 75-89-8
2,2,2-trifluoroethanol

: 13731-82-3
2,5-dibromoterephtalic acid

: 1268628-19-8
2,5-bis(2,2,2-trifluoroethoxy)terephthalic acid

Conditions

Conditions	Yield
Stage #1: 2,2,2-trifluoroethanol With sodium hydride In tetrahydrofuran Stage #2: 2,5-dibromoterephtalic acid; cis-N,N'-dimethyl-1,2-diaminocyclohexane; copper(ll) bromide In tetrahydrofuran; 2,2,2-trifluoroethanol at 60℃; for 96h; Stage #3: With hydrogenchloride In tetrahydrofuran; water	71%
Stage #1: 2,2,2-trifluoroethanol With sodium hydride In tetrahydrofuran Stage #2: 2,5-dibromoterephtalic acid; cis-N,N'-dimethyl-1,2-diaminocyclohexane; copper(ll) bromide In tetrahydrofuran; 2,2,2-trifluoroethanol at 60℃; for 96h; Stage #3: With hydrogenchloride In tetrahydrofuran; water	71%
Stage #1: 2,2,2-trifluoroethanol With sodium hydride In tetrahydrofuran Stage #2: 2,5-dibromoterephtalic acid; D,L-valine; copper(ll) bromide In tetrahydrofuran; 2,2,2-trifluoroethanol at 60℃; for 96h; Stage #3: With hydrogenchloride In tetrahydrofuran; water
Stage #1: 2,2,2-trifluoroethanol With sodium hydride In tetrahydrofuran Stage #2: 2,5-dibromoterephtalic acid; 1,2-bis[(2,4,6-trimethylphenyl)imino]-1,2-dimethylethane; copper(ll) bromide In tetrahydrofuran; 2,2,2-trifluoroethanol at 60℃; for 96h; Stage #3: With hydrogenchloride In tetrahydrofuran; water
Stage #1: 2,2,2-trifluoroethanol With sodium hydride In tetrahydrofuran Stage #2: 2,5-dibromoterephtalic acid; copper(ll) bromide In tetrahydrofuran; 2,2,2-trifluoroethanol at 60℃; for 96h; Stage #3: With hydrogenchloride In tetrahydrofuran; water

: 13731-82-3
2,5-dibromoterephtalic acid

: 108-67-8
1,3,5-trimethyl-benzene

: (2,5-dibromo-1,4-phenylene)bis(mesitylmethanone)

Conditions

Conditions	Yield
Stage #1: 2,5-dibromoterephtalic acid With thionyl chloride In dichloromethane for 24h; Reflux; Stage #2: 1,3,5-trimethyl-benzene With aluminum (III) chloride In dichloromethane at 0 - 20℃; for 12h;	70%
Stage #1: 2,5-dibromoterephtalic acid With thionyl chloride In dichloromethane for 12h; Reflux; Stage #2: 1,3,5-trimethyl-benzene With aluminum (III) chloride In dichloromethane Cooling with ice; Reflux;	65%

: 2425-77-6
2-hexyldecan-1-ol

: 13731-82-3
2,5-dibromoterephtalic acid

: 1,4-dibromo-2,5-bis(2-hexyldecanoate)benzene

Conditions

Conditions	Yield
Stage #1: 2,5-dibromoterephtalic acid With thionyl chloride Reflux; Stage #2: 2-hexyldecan-1-ol With pyridine at 80℃; for 18h;	70%

: 1134-35-6
4,4'-dimethyl-2,2'-bipyridines

: zinc(II) nitrate hexahydrate

: 13731-82-3
2,5-dibromoterephtalic acid

: C8H2Br2O4(2-)*C12H12N2*H2O*Zn(2+)

Conditions

Conditions	Yield
In water; N,N-dimethyl-formamide at 120℃; for 72h; Sealed tube;	70%

...Expand

: 13731-82-3
2,5-dibromoterephtalic acid

: 114460-21-8
calcium acetate hydrate

: 25372-07-0
1,4-bis-(1H-imidazol-1-yl)benzene

: (H2-dib)[Ca3(dbt)4(H2O)4·2H2O]n

Conditions

Conditions	Yield
With potassium hydroxide In ethanol; water at 120℃; for 72h; Sealed tube; High pressure;	69%

...Expand

: 553-26-4
4,4'-bipyridine

: uranyl nirate hexahydrate

: 13731-82-3
2,5-dibromoterephtalic acid

: [(uranyl)(2,5-dibromoterephthalate)(4,4′-bipyridine)0.5]

Conditions

Conditions	Yield
In ethanol; water at 160℃; for 24h; Sealed tube; High pressure;	65%

...Expand

: 366-18-7
[2,2]bipyridinyl

: cobalt(II) nitrate hexahydrate

: 13731-82-3
2,5-dibromoterephtalic acid

: C8H2Br2O4(2-)*C10H8N2*H2O*Co(2+)

Conditions

Conditions	Yield
In water; N,N-dimethyl-formamide at 120℃; for 72h; Sealed tube;	65%

...Expand

: 1004-38-2
2,4,6-triaminopyrimidine

: 13731-82-3
2,5-dibromoterephtalic acid

: 2C4H7N5*C8H4Br2O4

Conditions

Conditions	Yield
In ethanol; water for 0.5h;	63%

2,5-Dibromoterephthalic acid Chemical Properties

IUPAC Name: 2,5-dibromoterephthalic acid
Empirical Formula: C₈H₄Br₂O₄
Molecular Weight: 323.923g/mol
EINECS: 237-300-8
Structure of 1,4-Benzenedicarboxylicacid, 2,5-dibromo- (CAS NO.13731-82-3):

Index of Refraction: 1.679
Molar Refractivity: 55.49 cm³
Molar Volume: 146.8 cm³
Polarizability: 21.99×10^-24cm³
Surface Tension: 75.2 dyne/cm
Density: 2.205 g/cm³
Flash Point: 222.9 °C
Enthalpy of Vaporization: 74.08 kJ/mol
Melting Point: 320-325°C
Boiling Point: 445 °C at 760 mmHg
Vapour Pressure: 1.06E-08 mmHg at 25°C
Physical Appearance: white crystalline powder
Product Categories: Phthalic Acids, Esters and Derivatives;Carboxylic Acids;Phenyls & Phenyl-Het;Organic acids;Carboxylic Acids;Phenyls & Phenyl-Het;Derivatives of phthalic acid
Canonical SMILES: C1=C(C(=CC(=C1Br)C(=O)O)Br)C(=O)O
InChI: InChI=1S/C8H4Br2O4/c9-5-1-3(7(11)12)6(10)2-4(5)8(13)14/h1-2H,(H,11,12)(H,13,14)
InChIKey: VUTICWRXMKBOSF-UHFFFAOYSA-N

2,5-Dibromoterephthalic acid Safety Profile

Hazard Codes: Corrosive C, Irritant Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-37/39-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39:Wear suitable gloves and eye/face protection.
S36:Wear suitable protective clothing.

2,5-Dibromoterephthalic acid Specification

1,4-Benzenedicarboxylicacid, 2,5-dibromo- , its cas register number is 13731-82-3. It also can be called 2,5-Dibromoterephthalic acid ; NSC 115430 . 1,4-Benzenedicarboxylicacid, 2,5-dibromo- (CAS NO.13731-82-3) is irritating to eyes, respiratory system and skin.

Product Name

2,5-Dibromoterephthalic acid

Synthetic route

2,5-Dibromoterephthalic acid Chemical Properties

2,5-Dibromoterephthalic acid Safety Profile

2,5-Dibromoterephthalic acid Specification

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