2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide supplier

Name
2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide
EINECS 207-196-9
CAS No. 141776-47-8
Density 1.67 g/cm³
Solubility
Melting Point
Formula C₉H₁₁N₃O₄S₂
Boiling Point
Molecular Weight 289.336
Flash Point
Transport Information
Appearance White crystal
Safety
Risk Codes
Molecular Structure
Hazard Symbols Xi
Synonyms 2-(Ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide;
PSA 128.36000
LogP 2.63720

Synthetic route

: 2-ethylthioimidazo[1,2-a]pyridine-3-sulfonamide

: 141776-47-8
2-ethylsulfonylimidazo[1,2a]pyridine-3-sulfonamide

Conditions

Conditions	Yield
With 3-chloro-benzenecarboperoxoic acid In N-methyl-acetamide; water

: 89392-03-0
O-phenyl N-(4,6-dimethoxypyrimidin-2-yl)carbamate

: 141776-47-8
2-ethylsulfonylimidazo[1,2a]pyridine-3-sulfonamide

: N-(2-Ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)-N-(4,6-dimethoxy-2-pyrimidinyl)urea

Conditions

Conditions	Yield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile	91.3%

: 89402-43-7
5-chloro-2,3-difluoropyridine

: 94050-90-5
(R)-2-(4-hydroxyphenoxy)propionic acid

: 141776-47-8
2-ethylsulfonylimidazo[1,2a]pyridine-3-sulfonamide

: 1361405-60-8
(R)-2-ethanesulfonylimidazo[1,2-a]pyridine-3-sulfonic acid [2-[4-(5-chloro-3-fluoropyridin-2-yloxy)phenoxy]propionyl]amide

Conditions

Conditions	Yield
Stage #1: 5-chloro-2,3-difluoropyridine; (R)-2-(4-hydroxyphenoxy)propionic acid With potassium phosphate; tetra-(n-butyl)ammonium iodide In N,N-dimethyl-formamide at 50 - 60℃; for 2h; Stage #2: With 1,3,5-trichloro-2,4,6-triazine In N,N-dimethyl-formamide at 5 - 25℃; for 1.16667h; Stage #3: 2-ethylsulfonylimidazo[1,2a]pyridine-3-sulfonamide In N,N-dimethyl-formamide	74%

...Expand

: 616-45-5
2-pyrrolidinon

: 141776-47-8
2-ethylsulfonylimidazo[1,2a]pyridine-3-sulfonamide

: 2-(ethylsulfonyl)-N-(pyrrolidin-2-ylidene)imidazo[1,2-a]pyridine-3-sulfonamide

Conditions

Conditions	Yield
With diazoacetic acid ethyl ester; manganese(II) perchlorate hexahydrate In cyclohexane at 90℃; for 12h; chemoselective reaction;	58%

: 1885-14-9
phenyl chloroformate

: 141776-47-8
2-ethylsulfonylimidazo[1,2a]pyridine-3-sulfonamide

: 905926-26-3
C16H15N3O6S2

Conditions

Conditions	Yield
With triethylamine In acetonitrile at 3 - 20℃;

2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide Specification

The Imidazo[1,2-a]pyridine-3-sulfonamide,2-(ethylsulfonyl)-, with the CAS registry number 141776-47-8, is also known as 2-Ethylsulfonylimidazo[1,2-a]Pyridin-3-yl Sulfonamide. It belongs to the product category of Pyridines Derivates. This chemical's molecular formula is C₉H₁₁N₃O₄S₂ and molecular weight is 289.33. What's more, both its IUPAC name and systematic name are the same which is called 2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide. And it's white crystal.

Physical properties about Imidazo[1,2-a]pyridine-3-sulfonamide,2-(ethylsulfonyl)- are: (1) ACD/LogP: 0.38; (2) # of Rule of 5 Violations: 0; (3) ACD/LogD (pH 5.5): 0.03; (4) ACD/BCF (pH 5.5): 1; (5) ACD/BCF (pH 7.4): 1; (6) ACD/KOC (pH 5.5): 17.22; (7) ACD/KOC (pH 7.4): 1; (8) #H bond acceptors: 7; (9) #H bond donors: 2; (10) #Freely Rotating Bonds: 3; (11) Polar Surface Area: 128.36 Å²; (12) Index of Refraction: 1.706; (13) Molar Refractivity: 67.16 cm³; (14) Molar Volume: 172.5 cm³; (15) Surface Tension: 75.1 dyne/cm; (16) Density: 1.67 g/cm³.

When you are dealing with this chemical, you should be very careful. This chemical is irritant and may cause inflammation to the skin or other mucous membranes.

You can still convert the following datas into molecular structure:
(1) SMILES: CCS(=O)(=O)c1nc2ccccn2c1S(N)(=O)=O
(2) InChI: InChI=1/C9H11N3O4S2/c1-2-17(13,14)8-9(18(10,15)16)12-6-4-3-5-7(12)11-8/h3-6H,2H2,1H3,(H2,10,15,16)
(3) InChIKey: MJVXHAPMFSPZRH-UHFFFAOYAF

Product Name

2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide

Synthetic route

2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide Specification

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