Product Name

  • Name

    2-Methylphenyl isocyanate

  • EINECS 210-389-0
  • CAS No. 614-68-6
  • Article Data54
  • CAS DataBase
  • Density 1.074
  • Solubility Hydrolyzes in water.
  • Melting Point
  • Formula C8H7 N O
  • Boiling Point 185.7 °C at 760 mmHg
  • Molecular Weight 133.15
  • Flash Point 92 ºC
  • Transport Information UN 2206 6
  • Appearance clear colorless to light yellow liquid
  • Safety 23-26-45-36/37/39
  • Risk Codes R20/21/22;R36/37/38   
  • Molecular Structure Molecular Structure of 614-68-6 (2-Methylphenyl isocyanate)
  • Hazard Symbols
  • Synonyms Isocyanicacid, o-tolyl ester (7CI,8CI); 1-Isocyanato-2-methylbenzene; 2-Methylphenylisocyanate; 2-Tolyl isocyanate; o-Methylphenyl isocyanate; o-Tolueneisocyanate; o-Tolyl isocyanate
  • PSA 29.43000
  • LogP 1.96230

2-Methylphenyl isocyanate Chemical Properties

IUPAC Name: 2-Methylphenyl isocyanate  
CAS: 614-68-6
Formula : C8H7NO
Molecular Weight: 133.15
Molecular Structure of 2-Methylphenyl isocyanate (614-68-6):

Density: 0.99 g/cm3 
Flash Point: 92.2 °C
Boiling Point: 185.7 °C at 760 mmHg  
Index of Refraction: 1.518
Appearance: clear colorless to light yellow liquid 
Molar Refractivity: 40.58 cm3 
Molar Volume: 133.7 cm3 
Polarizability: 16.08×10-24cm3 
Surface Tension: 35.4 dyne/cm 
Enthalpy of Vaporization: 42.19 kJ/mol 
Vapour Pressure: 0.689 mmHg at 25°C 
Water Solubility: 185.9(mg/L) at 25°C

2-Methylphenyl isocyanate Toxicity Data With Reference

1.    

orl-rat LD50:1600 mg/kg

    NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) OTS0528340 .
2.    

ihl-rat LCLo:88 ppm/6H

    NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) OTS0528340 .
3.    

ipr-rat LD50:50 mg/kg

    NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) OTS0528340 .
4.    

orl-gpg LD50:400 mg/kg

    NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) OTS0528340 .
5.    

ipr-gpg LD50:200 mg/kg

    NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) OTS0528340 .

2-Methylphenyl isocyanate Safety Profile

A poison by inhalation and intraperitoneal routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx.
Safety Information about 2-Methylphenyl isocyanate (614-68-6):
Hazard Codes:
Xn:
Xi: 
Risk Statements about 2-Methylphenyl isocyanate (614-68-6):
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.
R42: During fumigation/spraying wear suitable respiratory equipment (appropriate wording to be specified).
Safety Statements about 2-Methylphenyl isocyanate (614-68-6): 
S23: Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer).
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible).
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
RIDADR: UN 2206 6.1/PG 2
WGK Germany: 3
RTECS: DA3678333
F19: Lachrymator.
F21: Sensitive to humidity.
Hazard Note: Irritant
HazardClass: 6.1
PackingGroup: II

2-Methylphenyl isocyanate Specification

Some useful infamation about  the operate and store of the product
The chemical synonyms of 2-Methylphenyl isocyanate (614-68-6) are Isocyanato-2-methylbenzene ; Methylphenyl isocyanate ; 2-Tolyl isocyanate o-Methylphenyl isocyanate ; o-Toluene isocyanate ; o-Tolyl isocyanate .It's may causes eye irritation. Lachrymator (substance which increases the flow of tears).causes skin irritation. Harmful if absorbed through the skin.Harmful if swallowed. May cause irritation of the digestive tract. 
Harmful if inhaled. Causes respiratory tract irritation. Inhalation may produce burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting.so it shoud avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes and keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container.It can be used for organic reagent and pharmaceutical intermediate.

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