3,4-DIFLUOROBENZENESULFONYL CHLORIDE

The 3,4-Difluorobenzenesulfonyl chloride, with the CAS registry number 145758-05-0, is a kind of moisture sensitive chemical, and belongs to the following product categories: Sulfonyl halide; Aromatic Halides (substituted); Benzenesulfonyl chloride; Organic Building Blocks; Sulfonyl Halides; Sulfur Compounds. Besides, the molecular formula of this chemical is F₂C₆H₃SO₂Cl.

The physical properties of 3,4-Difluorobenzenesulfonyl chloride are as following: (1)ACD/LogP: 2.63; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.63; (4)ACD/LogD (pH 7.4): 2.63; (5)ACD/BCF (pH 5.5): 58.89; (6)ACD/BCF (pH 7.4): 58.89; (7)ACD/KOC (pH 5.5): 643.62; (8)ACD/KOC (pH 7.4): 643.62; (9)#H bond acceptors: 2; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 42.52 Å²; (13)Index of Refraction: 1.515; (14)Molar Refractivity: 40.62 cm³; (15)Molar Volume: 134.5 cm³; (16)Polarizability: 16.1×10^-24cm³; (17)Surface Tension: 39.3 dyne/cm; (18)Density: 1.58 g/cm³; (19)Flash Point: 109.9 °C; (20)Enthalpy of Vaporization: 47.57 kJ/mol; (21)Boiling Point: 258.1 °C at 760 mmHg; (22)Vapour Pressure: 0.0226 mmHg at 25°C.

Preparation of 3,4-Difluorobenzenesulfonyl chloride: This chemical can be prepared by 1,2-difluoro-benzene. The reaction will need reagent chlorosulfonic acid. The reaction time is 0.5 hours with temperature of 80°C. 

Uses of 3,4-Difluorobenzenesulfonyl chloride: It can be used to produce 3,4-difluorobenzenesulfonamide. This reaction will need reagents conc. NH₄OH with 0.5 hours.

You should be cautious while dealing with this chemical. It may cause burns. Therefore, you had better take the following instructions: Wear suitable protective clothing, gloves and eye/face protection, and in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice; In case of accident or if you feel unwell, seek medical advice immediately (show label where possible).

You can still convert the following datas into molecular structure:
(1)SMILES: Fc1ccc(cc1F)S(Cl)(=O)=O
(2)InChI: InChI=1/C6H3ClF2O2S/c7-12(10,11)4-1-2-5(8)6(9)3-4/h1-3H
(3)InChIKey: FSGLUBQENACWCC-UHFFFAOYAX