4,7-Dichloro-2-methylquinoline

The 4, 7-Dichloro-2-methylquinoline, with the CAS registry number 50593-69-6, is also known as Quinoline, 4, 7-dichloro-2-methyl-. This chemical's molecular formula is C₁₀H₇Cl₂N and molecular weight is 212.08. What's more, its systematic name is 4, 7-Dichloro-2-methylquinoline.

Physical properties about 4, 7-Dichloro-2-methylquinoline are: (1)ACD/LogP: 3.92; (2)# of Rule of 5 Violations: 0; (3)#H bond acceptors: 1; (4)#H bond donors: 0; (5)#Freely Rotating Bonds: 0; (6)Polar Surface Area: 12.89 Å²; (7)Index of Refraction: 1.643; (8)Molar Refractivity: 56.8 cm³; (9)Molar Volume: 156.9 cm³; (10)Polarizability: 22.51×10^-24 cm³; (11)Surface Tension: 48.7 dyne/cm; (12)Density: 1.351 g/cm³; (13)Flash Point: 164.4 °C; (14)Enthalpy of Vaporization: 51.98 kJ/mol; (15)Boiling Point: 301.3 °C at 760 mmHg; (16)Vapour Pressure: 0.0019 mmHg at 25 °C.

Preparation of 4, 7-Dichloro-2-methylquinoline: this chemical is prepared by 7-Chloro-2-methyl-quinolin-4-ol by heating. The reaction needs reagent POCl₃. The reaction time is 1 hour with reaction temperature of 120 °C. The yield is about 80 %.

Uses of 4, 7-Dichloro-2-methylquinoline: it is used to produce other chemicals. For example, it is used to produce 4, 7-Dichloro-2-[4-(5-nitro-furan-2-yl)-buta-1, 3-dienyl]-quinoline. The reaction needs reagent ZnCl₂. The reaction temperature is 135-155 °C. The yield is about 82.4 %.

You can still convert the following datas into molecular structure:
(1) SMILES: Clc1cc2nc(cc(Cl)c2cc1)C
(2) InChI: InChI=1/C10H7Cl2N/c1-6-4-9(12)8-3-2-7(11)5-10(8)13-6/h2-5H,1H3
(3) InChIKey: QTYCALFKBCOYLW-UHFFFAOYAK