Product Name

  • Name

    5'-THYMIDYLIC ACID DISODIUM SALT

  • EINECS 251-518-0
  • CAS No. 365-07-1
  • Article Data88
  • CAS DataBase
  • Density 1.654 g/cm3
  • Solubility
  • Melting Point
  • Formula C10H15N2O8P
  • Boiling Point
  • Molecular Weight 322.211
  • Flash Point
  • Transport Information
  • Appearance white crystalline powder
  • Safety
  • Risk Codes
  • Molecular Structure Molecular Structure of 365-07-1 (5'-THYMIDYLIC ACID DISODIUM SALT)
  • Hazard Symbols
  • Synonyms 2'-Deoxythymidine5'-monophosphate;5-Methyl-dUMP;5'-TMP;5'-dTMP;Deoxy TMP;Deoxyribosylthymine monophosphate;Deoxythymidine 5'-monophosphate;Deoxythymidine 5'-phosphate;Deoxythymidine monophosphate;Deoxythymidinephosphate;Deoxythymidylic acid;NSC 46713;TMP (nucleotide);Thymidine5'-(dihydrogen phosphate);Thymidine 5'-monophosphate;Thymidine 5'-phosphate;Thymidine 5'-phosphoric acid;Thymidine mononucleotide;Thymidinemonophosphate;Thymidine phosphate;Thymidine, mono(dihydrogen phosphate)(ester);Thymidine-5'-monophosphoric acid;Thymidylic acid;dTMP;
  • PSA 160.89000
  • LogP -1.39730

5'-Thymidylic acid Specification

This chemical is called 5'-Thymidylic acid, and it can also be named as Thymidine 5'-monophosphate. With the molecular formula of C10H15N2O8P, its molecular weight is 322.21. The CAS registry number of this chemical is 365-07-1, and its IUPAC name is [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl dihydrogen phosphate. 

Other characteristics of the 5'-Thymidylic acid can be summarised as followings: (1)ACD/LogP: -1.60; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): -4.93; (4)ACD/LogD (pH 7.4): -5.87; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 10; (10)#H bond donors: 4; (11)#Freely Rotating Bonds: 5; (12)Polar Surface Area: 113.65 Å2; (13)Index of Refraction: 1.592; (14)Molar Refractivity: 65.99 cm3; (15)Molar Volume:194.8 cm3; (16)Polarizability: 26.16×10-24 cm3; (17)Surface Tension: 77 dyne/cm; (18)Density: 1.654 g/cm3.

Production method of this chemical: The 5'-Thymidylic acid could be obtained by the reactant of thymidine. This reaction needs the reagent of p-nitrophenyl phosphate. The yield is 82 %. This reaction should be taken at the temperature of 50 °C. The other condition is Erwina herbicola 47/3 cells.

The 5'-Thymidylic acid could be obtained by the reactant of thymidine.

Uses of this chemical: The [5']thymidylic acid monomethyl ester could be obtained by the reactants of 5'-Thymidylic acid and methanol. This reaction needs the reagents of dicyclohexylcarbodiimide and pyridine. The yield is 66 %. This reaction should be taken for 24 hours at the temperature of 30 °C.

The [5']thymidylic acid monomethyl ester could be obtained by the reactants of 5'-Thymidylic acid and methanol.

You can still convert the following datas into molecular structure:
1.SMILES: O=P(O)(O)OC[C@H]2O[C@@H](N\1C(=O)NC(=O)/C(=C/1)C)C[C@@H]2O
2.InChI: InChI=1/C10H15N2O8P/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(20-8)4-19-21(16,17)18/h3,6-8,13H,2,4H2,1H3,(H,11,14,15)(H2,16,17,18)/t6-,7+,8+/m0/s1
3.InChIKey: GYOZYWVXFNDGLU-XLPZGREQBM

Related Products

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View