Acid blue 25 supplier | CasNO.6408-78-2

Name
ACID BLUE 25
EINECS 229-068-1
CAS No. 6408-78-2
Article Data13
CAS DataBase
Density 1.491[at 20℃]
Solubility Soluble in acetone and alcohol, slightly soluble in benzene and tetralin
Melting Point >300ºC
Formula C₂₀H₁₄N₂O₅S.Na
Boiling Point 846.88℃[at 101 325 Pa]
Molecular Weight 416.389
Flash Point
Transport Information
Appearance Blue powder
Safety 26-36
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms C.I. Acid blue 25;2-Anthracenesulfonic acid, 1-amino-9,10-dihydro-9,10-dioxo-4-(phenylamino)-, monosodium salt;Sodium 1-amino-9,10-dioxo-4-phenylaminoanthracene-2-sulphonate;Sodium 1-amino-4-anilino-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate;CHEMBL256057;210684_SIAL;CID22915;1-Amino-4-anilino-9,10-dioxoanthracene-2-sulfonate;
PSA 137.77000
LogP 4.42690

Synthetic route

: 6258-06-6
sodium 1-amino-4-bromoanthraquinone-2-sulfonate

: 62-53-3
aniline

: 6408-78-2
acid blue 25

Conditions

Conditions	Yield
With copper In aq. phosphate buffer at 80℃; for 0.333333h; pH=6 - 7; Microwave irradiation;	90%
With disodium hydrogenphosphate; sodium dihydrogenphosphate; copper In water at 80℃; for 0.333333h; Microwave irradiation;	90%
With sodium carbonate; copper(II) sulfate In water at 90℃; for 48h; Ullmann coupling;	60%

: 6258-06-6
sodium 1-amino-4-bromoanthraquinone-2-sulfonate

: 62-53-3
aniline

A: 25492-62-0
sodium 1-amino-4-hydroxy-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate

B: 6408-78-2
acid blue 25

Conditions

Conditions	Yield
With disodium hydrogenphosphate; sodium dihydrogenphosphate; copper In water at 80℃; under 7500.75 Torr; for 0.0833333h; pH=6 - 7; Ullmann coupling reaction; microwave irradiation;	A n/a B 55%

...Expand

: 116-81-4
1-amino-4-bromo-9,10-dioxoanthracene-2-sulphonic acid

: 62-53-3
aniline

: 6408-78-2
acid blue 25

Conditions

Conditions	Yield
With copper Ullmann reaction; aq. phosphate buffer; Microwave irradiation; Heating;

: 143-33-9
sodium cyanide

: 6408-78-2
acid blue 25

: 86397-45-7
1-amino-9,10-dioxo-4-phenylamino-9,10-dihydroanthracene-2,3-dicarbonitrile

Conditions

Conditions	Yield
With ammonium bicarbonate 1.) DMSO, 100 deg C, 15 h; 2.) water, r.t., 4 h;	96%

: 6408-78-2
acid blue 25

: 128-95-0
1,4-diamino-9,10-anthraquinone

Conditions

Conditions	Yield
With hydrogenchloride; acetic acid; tin(ll) chloride for 3h; Heating;	89%

: 6408-78-2
acid blue 25

: 102160-11-2
4-phenylamino-9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid

Conditions

Conditions	Yield
Stage #1: acid blue 25 With hydrogenchloride; water; sodium nitrite at 0 - 20℃; Stage #2: With ethanol; zinc at 20℃; for 0.00833333h;	79%

: 64-17-5
ethanol

: 31165-67-0
2'-benzyloxyacetophenone

: 6408-78-2
acid blue 25

: 698355-95-2
C37H28N2O3

Conditions

Conditions	Yield
With potassium hydroxide for 2h; Heating / reflux;	32.7%

...Expand

: 112-53-8
1-dodecyl alcohol

: 6408-78-2
acid blue 25

sodium hydroxide: sodium hydroxide

: 1-amino-4-anilino-2-dodecyloxy-anthraquinone

Conditions

Conditions	Yield
at 120℃;
at 120℃;

...Expand

: 6408-78-2
acid blue 25

: 6471-06-3
sodium salt of 1,4-diaminoanthraquinone-2-sulfonic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 89 percent / acetic acid; SnCl2; HCl / 3 h / Heating 2: 51 percent / chlorosulfonic acid; Na2CO3 / nitrobenzene / 3 h / 130 °C View Scheme

: 6408-78-2
acid blue 25

: 32571-82-7
1-Amino-9,10-dioxo-4-phenylamino-9,10-dihydroanthracen-2-carbonitril

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 96 percent / 1.) ammonium hydrogen carbonate / 1.) DMSO, 100 deg C, 15 h; 2.) water, r.t., 4 h 2: 1.2 g / 0.08 h / 160 °C View Scheme
Multi-step reaction with 2 steps 1: 96 percent / 1.) ammonium hydrogen carbonate / 1.) DMSO, 100 deg C, 15 h; 2.) water, r.t., 4 h 2: 1.2 g / 2-amino-ethanol / 0.08 h / 160 °C View Scheme

: 6408-78-2
acid blue 25

: 4-Amino-3-hydroxy-9,10-dioxo-1-phenylamino-9,10-dihydroanthracen-2-carbonitril

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 96 percent / 1.) ammonium hydrogen carbonate / 1.) DMSO, 100 deg C, 15 h; 2.) water, r.t., 4 h 2: 3.1 g / 30percent aq. NaOH / pyridine / 2 h / 100 °C View Scheme

: 6408-78-2
acid blue 25

: 1-Amino-2-(Δ2-1,3-oxazolin-2-yl)-4-(phenylamino)anthrachinon

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 96 percent / 1.) ammonium hydrogen carbonate / 1.) DMSO, 100 deg C, 15 h; 2.) water, r.t., 4 h 2: 1.2 g / 0.08 h / 160 °C 3: 3.1 g / 1,2-dichloro-benzene / 24 h / 160 °C View Scheme
Multi-step reaction with 3 steps 1: 96 percent / 1.) ammonium hydrogen carbonate / 1.) DMSO, 100 deg C, 15 h; 2.) water, r.t., 4 h 2: 1.2 g / 0.08 h / 160 °C 3: 0.14 g / nitrobenzene / 24 h / 160 °C View Scheme
Multi-step reaction with 2 steps 1: 96 percent / 1.) ammonium hydrogen carbonate / 1.) DMSO, 100 deg C, 15 h; 2.) water, r.t., 4 h 2: 0.15 g / 0.08 h / 160 °C View Scheme

: 6408-78-2
acid blue 25

: 4-Amino-3-(2-hydroxyaethylamino)-9,10-dioxo-1-phenylamino-9,10-dihydroanthracen-2-carbonitril

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 96 percent / 1.) ammonium hydrogen carbonate / 1.) DMSO, 100 deg C, 15 h; 2.) water, r.t., 4 h 2: 0.16 g / 0.08 h / 160 °C View Scheme
Multi-step reaction with 2 steps 1: 96 percent / 1.) ammonium hydrogen carbonate / 1.) DMSO, 100 deg C, 15 h; 2.) water, r.t., 4 h 2: 2 g / pyridine / 48 h / Ambient temperature View Scheme
Multi-step reaction with 2 steps 1: 96 percent / 1.) ammonium hydrogen carbonate / 1.) DMSO, 100 deg C, 15 h; 2.) water, r.t., 4 h 2: 0.16 g / 2-amino-ethanol / 0.08 h / 160 °C View Scheme

: 6408-78-2
acid blue 25

: 1-Amino-2-(benzimidazol-2'-yl)-4-(phenylamino)anthrachinon

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 96 percent / 1.) ammonium hydrogen carbonate / 1.) DMSO, 100 deg C, 15 h; 2.) water, r.t., 4 h 2: 1.2 g / 0.08 h / 160 °C 3: 1.26 g / nitrobenzene / 24 h / 160 °C View Scheme
Multi-step reaction with 3 steps 1: 96 percent / 1.) ammonium hydrogen carbonate / 1.) DMSO, 100 deg C, 15 h; 2.) water, r.t., 4 h 2: 1.2 g / 2-amino-ethanol / 0.08 h / 160 °C 3: 1.26 g / nitrobenzene / 24 h / 160 °C View Scheme

: 6408-78-2
acid blue 25

: 1-Amino-9,10-dioxo-4-phenylamino-2-(1'H-tetrazol-5'-yl)9,10-dihydroanthracen-3-carbonitril

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 96 percent / 1.) ammonium hydrogen carbonate / 1.) DMSO, 100 deg C, 15 h; 2.) water, r.t., 4 h 2: 4 g / NaN3, NH4Cl / dimethylformamide / 15 h / 80 °C View Scheme

: 6408-78-2
acid blue 25

: 4-Amino-3-(3-(dimethylamino)propylamino)-9,10-dioxo-1-phenylamino-9,10-dihydroanthracen-2-carbonitril

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 96 percent / 1.) ammonium hydrogen carbonate / 1.) DMSO, 100 deg C, 15 h; 2.) water, r.t., 4 h 2: 2.8 g / 24 h / Ambient temperature View Scheme

: 6408-78-2
acid blue 25

: 94-02-0
ethyl 3-oxo-3-phenylpropionate

: 1388148-81-9
C29H17N2O6S(1-)*Na(1+)

Conditions

Conditions	Yield
With sodium carbonate In dimethyl sulfoxide; 1,2-dichloro-benzene at 170 - 172℃; for 4h;

: 6408-78-2
acid blue 25

: 94-02-0
ethyl 3-oxo-3-phenylpropionate

: C29H14N2O15S4(4-)*4Na(1+)

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: sodium carbonate / 1,2-dichloro-benzene; dimethyl sulfoxide / 4 h / 170 - 172 °C 2.1: sulfur trioxide; sulfuric acid / 3 h / 85 - 90 °C 2.2: 1 h / 40 - 45 °C View Scheme

: 6408-78-2
acid blue 25

: C20H11N3O5S*Na(1+)

Conditions

Conditions	Yield
With sulfuric acid; acetic acid; sodium nitrite at 5 - 10℃;

Acid blue 25 Specification

The Acid blue 25 with CAS registry number of 6408-78-2 is also known as 2-Anthracenesulfonic acid, 1-amino-9,10-dihydro-9,10-dioxo-4-(phenylamino)-, monosodium salt. The IUPAC name is sodium 1-Amino-4-anilino-9,10-dioxoanthracene-2-sulfonate. It belongs to product categories of Dyes and Pigments; Organics; A; Stains and Dyes; Stains&Dyes, A to. Its EINECS registry number is 229-068-1. In addition, the formula is C₂₀H₁₄N₂O₅S.Na and the molecular weight is 417.38. This chemical is a blue powder and should be stored in cool , dry place.

Physical properties about Acid blue 25 are: (1)ACD/LogP: 2.62; (2)ACD/LogD (pH 5.5): -0.88; (3)ACD/LogD (pH 7.4): -0.89; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 1; (7)ACD/KOC (pH 7.4): 1; (8)#H bond acceptors: 7; (9)#H bond donors: 4; (10)#Freely Rotating Bonds: 4; (11)Polar Surface Area: 103.37Å².

Preparation of Acid blue 25: it is prepared by reaction of bromine acid with aniline. The reaction occurs with reagents Na₂CO₃, CuSO₄, solvent H₂O and catalyst Tai salt at the temperature of 90 °C. At last, product is obtained by filtration and drying.

Uses of Acid blue 25: it is mainly used for silk, wool, nylon and blended fabric dyeing. What's more, it is used to produce 1-amino-9,10-dioxo-4-phenylamino-9,10-dihydroanthracene-2,3-dicarbonitrile by reaction with hydrocyanic acid; sodium salt. The reaction occurs with reagent ammonium hydrogen carbonate in two steps. The first step needs DMSO at 100 °C while the second step occurs with r.t. in water for 4 hours. The yield is about 96%.

Acid blue 25 is used to produce 1-amino-9,10-dioxo-4-phenylamino-9,10-dihydroanthracene-2,3-dicarbonitrile by reaction with hydrocyanic acid; sodium salt.

When you are using this chemical, please be cautious about it. As a chemical, it is irritating to eyes, respiratory system and skin. During using it, wear suitable protective clothing. If contact with eyes accidently, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
1. Canonical SMILES: C1=CC=C(C=C1)NC2=CC(=C(C3=C2C(=O)C4=CC=CC=C4C3=O)N)S(=O)(=O)[O-].[Na+]
2. InChI: InChI=1S/C20H14N2O5S.Na/c21-18-15(28(25,26)27)10-14(22-11-6-2-1-3-7-11)16-17(18)20(24)13-9-5-4-8-12(13)19(16)23;
/h1-10,22H,21H2,(H,25,26,27);/q;+1/p-1
3. InChIKey: LIKZXCROQGHXTI-UHFFFAOYSA-M

Product Name

ACID BLUE 25

Synthetic route

Acid blue 25 Specification

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